Treatment of Pleural and Peritoneal Carcinosis with Radioactive Colloids

  • G. Riccabona
Conference paper

Abstract

The concept of treating effusions due to pleura or peritoneal carcinosis with radioactive colloids was introduced 40 years ago [2]. For this purpose, 63Zn sulfide and later on 198Au colloid have been used [2, 3]. Both cases involved the application of beta and gamma emitters, where the beta emission was almost exclusively responsible for the therapeutic effect. As the gamma radiation necessitated inconvenient precautions for radiation protection [1], radioactive colloids with pure beta emission have been developed since 1954 for intracavitary radionuclide therapy [4–7]. This concerned primarily 32P chromium phosphate and 90Y silicate; 169Er citrate and 186Re sulfate were also recommended. Whereas the two latter compounds were not applied on a large scale, the 90Y colloid has for almost 30 years proved to be the most suitable substance for the treatment of malignant effusions in pleura and peritoneum.

Keywords

Sulfide Silicate Chromium Citrate Radionuclide 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • G. Riccabona
    • 1
  1. 1.Universitätsklinik für NuklearmedizinInnsbruckAustria

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