Vision Research: Raman/Fluorescence Studies on Aging and Cataract Formation in the Lens

  • Nai-Teng Yu
  • Brent C. Barron
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)


The ocular lens is a crystallin, parabolic, avascular tissue surrounded by a structureless semipermeable capsule. When the lens capsule is fully developed in the fetal state, all interchanges, between the lens and the surrounding tissues and humors cease. This development gives rise to an embryonic nucleus which will be present throughout the lifetime of the animal. Underlying the capsule on the anterior side of the lens is a monolayer of epithelium cells which give rise to all lens fibers. The epithelium cells in the equatorial zone, the region with the highest mitotic rate, elongate and become lens fibers with a concomitant loss of nuclei and cellular organelles. During this process the newer fibers displace and compress the older fibers toward the nucleus of the lens. The nucleus is, thus, composed of the oldest fibers and is the most dense.


Cataract Formation Human Lens Visual Axis Lens Protein Senile Cataract 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • Nai-Teng Yu
  • Brent C. Barron
    • 1
    • 2
    • 3
  1. 1.School of ChemistryEmory UniversityAtlantaUSA
  2. 2.Georgia Institute of TechnologyEmory UniversityAtlantaUSA
  3. 3.Department of OphthalmologyEmory UniversityAtlantaUSA

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