Abstract
Nearly 100 years ago Langley (1905) introduced the idea of a specific, receptive substance to explain the competitive action of nicotine and curare at the neuromuscular junction. The operational concept of the receptor proved to be necessary in comprehending the specificity and mode of action of hormones, neurotransmitters, and drugs. Besides those receptors that are of special pharmacological importance and for which rather strict definitions are accepted (Bockaert 1978), the concept may also be applied to the phenomena of chemotaxis and nutrient transport through membranes, insect chemical communication, and intercell recognition and communication. In this lecture we shall be dealing mainly with the neurotransmitter, hormone, and drug receptors located in the cell membrane, but most of the open problems are common to the broader concept of receptors.
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Hadži, D. (1986). Receptors — What We Know and What We Wish to Know. In: Pifat-Mrzljak, G. (eds) Supramolecular Structure and Function. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70905-0_1
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DOI: https://doi.org/10.1007/978-3-642-70905-0_1
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