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Role of Metabolism in Pesticide Selectivity and Toxicity

  • S. D. Murphy
Conference paper
Part of the NATO ASI Series book series (volume 13)

Abstract

Ideally, pesticides will be selectively toxic to target organisms and non-toxic to non-target or desirable organisms. Theoretically, this might be achieved by several means. First, a pesticidal chemical might be designed or selected which uniquely attacks a functional or structural bio-system that is peculiar to the pest organism and which is either absent in or less critical to the desirable organism. Examples of this would include: the use of red squill as a rodenticide, particularly useful because rats do not effectively vomit the material whereas other mammals do; or the use of chitin synthetase inhibitors which are selectively toxic to invertebrates with exoskeleton and nontoxic, or generally much less toxic, to mammalian organisms; or the use of juvenile hormones which affect the peculiar metamorphic development of insects.

Keywords

Methyl Parathion Organophosphate Insecticide Mixed Function Oxidase Nontarget Species Piperonyl Butoxide 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • S. D. Murphy
    • 1
  1. 1.Department of Environmental Health, SC-34, School of Public Health and Community MedicineUniversity of WashingtonSeattleUSA

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