Can Mode of Action Studies Guide Chemical Synthesis?

  • T. A. Miller
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

Chemical industry has been exploring alternative means of finding new insecticides to supplement traditional screening of chemicals. The need to reexamine the means of finding active compounds was brought about partly by a decreased success rate coming from straightforward bioassay screens (Menn 1983) and partly by the realization that much activity could well have been missed in the past. This is particularly true of behavior-modifying chemicals when screens are designed only to detect toxicity.

Keywords

Lactone Benzimidazole Cholinesterase Carbamate Rotenone 

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • T. A. Miller
    • 1
  1. 1.Division of Toxicology and Physiology, Department of EntomologyUniversity of CaliforniaRiversideUSA

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