Hemodynamic Effects and Mechanism of Action of Dihydroergotamine in Epidural Anesthesia
Relative cardiovascular stability has been found to be one of the major advantages of epidural anesthesia and, depending on the nature of the case, a moderate degree of hypotension may be tolerated before a correction becomes necessary. However, if the arterial pressure declines, it may be difficult to compensate for the dilated vascular bed resulting from sympathetic paralysis by means of fluid substitution alone. Impairment of circulatory compensatory mechanisms, activated by a decrease in perfusion pressure, may necessitate immediate treatment if the venous return is restricted by a loss of effective blood volume from hemorrhage or by postural pooling in regions of vasodilatation.
KeywordsPulmonary Artery Pressure Epidural Anesthesia Hemodynamic Effect Femoral Flow Total Peripheral Resistance
Unable to display preview. Download preview PDF.
- 4.Bromage PR (1978) Epidural Analgesia. Saunders, PhiladelphiaGoogle Scholar
- 6.Clark BJ, Chu D, Aellig WH (1978) In: Berde B, Schild HO (eds) Ergot alkaloids and related compounds. Springer, Berlin Heidelberg New York, p 65 (Handbook of experimental pharmacology, vol 49)Google Scholar
- 11.Zimpfer M, Fitzal S, Tonczar L (1979) Aufhebung des Blutdruckabfalls bei Spinalanaesthesie durch Dihydroergotamin (DHE). Region Anaesth 2:43–47Google Scholar
- 12.Zimpfer M, Fitzal S, Ilias W, Raberger G, Stanek B (1980) Cardiovascular effects of dihydroergotamine in high epidural analgesia and mild acute hypovolemia. Region Anaesth 5:11–14Google Scholar