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Effects of a Single I.V. Dose of Nicergoline on Haemorrheological and Haemodynamic Parameters in Peripheral Vascular Disease. A Double-Blind, Cross-over Study

  • T. Di Perri
  • M. Guerrini
  • R. Cappelli
  • A. Acciavatti
  • D. Peera-Galli
  • S. Pecchi
  • G. Sacchetti
  • S. Forconi

Abstract

Peripheral obliterative arterial disease (POAD) is a clinical condition characterized from a pathophysiological point of view by a reduction of nutritional blood flow due to atherosclerotic stenosis or occlusion of great or medium-sized arteries of the legs. In this condition, blood flow supply to the tissue can be insufficient to meet the metabolic needs and ischaemia can occur. The blood flow reduction usually develops slowly and a compensatory mechanism can be activated to antagonize ischaemia.

Keywords

Peak Flow Blood Viscosity Ergot Alkaloid Haemodynamic Parameter Blood Filterability 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • T. Di Perri
    • 1
  • M. Guerrini
    • 1
  • R. Cappelli
    • 1
  • A. Acciavatti
    • 1
  • D. Peera-Galli
    • 1
  • S. Pecchi
    • 1
  • G. Sacchetti
    • 2
  • S. Forconi
    • 1
  1. 1.Istituto di Patologia Speciale MedicaUniversità di SienaSienaItaly
  2. 2.Medical Department, Pharmaceutical DivisionFarmitalia Carlo ErbaMilanoItaly

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