Studies into the raf and Rif Genes in the Mouse
My laboratory has been interested in the mechanisms underlying the regulated expression of the murine albumin and α-fetoprotein (AFP) genes in the mouse. These genes are located on chromosome 5 in the mouse, with the 18 kilobase pair (Kb) long albumin gene 14 kb upstream of the 22 kb AFP gene (D’Eustachio et al 1981; Ingram et al 1981). Structural comparisons between the two genes in several species have unequivocably established their evolutionary relationship.
KeywordsVisceral Endoderm Albumin Gene Autosomal Recessive Gene Fetal Mouse Liver High Stringency Hybridization
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