Isotype-Specific Interactions Between Regulatory T Cells and Secreted and Membrane-Bound Monoclonal Immunoglobulins
Previous studies have established that elements of the immunoregulatory system of the mouse can be directed to plasmacytoma cells in vivo and in vitro and influence their growth, differentiation and immunoglobulin expression. Those studies, which have been reviewed elsewhere (Lynch, 1979), have shown that certain murine plasmacytomas can respond to antigen-specific and idiotype-specific helper and suppressor T cells.
KeywordsSplenic Lymphocyte Monoclonal Immunoglobulin Plasmacytoma Cell Immunoregulatory System Immunoglobulin Heavy Chain Class
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