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Immunological Tolerance in BALB/c Mice

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 122))

Abstract

Idiosyncratic behaviour of adult BALB/c mice subjected to tolerization schedules has been observed with two dissimilar systems using heterologous γ-globulins and the α1 → 3 glucosyl epitope of dextran B1355 as tolerogens.

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References

  • Blomberg B, Geckeler WR, Weigert M (1972) Genetics of the antibody response to dextran in mice. Science 177:178–180

    Article  PubMed  CAS  Google Scholar 

  • Chaouat G, Howard JG (1976) Influence of reticuloendothelial blockade on the induction of tolerance and immunity by polysaccharides. Immunology 30:221–227

    PubMed  CAS  Google Scholar 

  • Cowing C, Harris D, Garabedian C, Lukic M, Leskowitz S (1977) Immunologic tolerance to heterologous immunoglobulin: its relation toin vitro filtration by macrophages. J Immunol 119:256–262

    PubMed  CAS  Google Scholar 

  • Das S, Dipadua D, Leskowitz S (1973) Tolerance induction with aggregated bovine gamma globulin in C57BI/6 mice (37594). Proc Soc Exp Biol Med 144:373–375

    PubMed  CAS  Google Scholar 

  • Das S, Leskowitz S (1974) The cellular basis for tolerance or immunity to bovine γ-globulin in mice. J Immunol 112:107–114

    PubMed  CAS  Google Scholar 

  • Dresser DW (1962) Specific inhibition of antibody production. II. Paralysis induced in adult mice by small quantities of protein antigen. Immunology 5:378–388

    PubMed  CAS  Google Scholar 

  • Frei PC, Benacerraf B, Thorbecke GJ (1965) Phagocytosis of the antigen, a crucial step in the induction of the primary response. Proc Nat Acad Sci 53:20–23

    Article  PubMed  CAS  Google Scholar 

  • Golub ES, Weigle WO (1969) Studies on the induction of immunologic unresponsiveness. III. Antigen form and mouse strain variation. J Immunol 102:389–396

    PubMed  CAS  Google Scholar 

  • Howard JG, Courtenay BM, Vicari G (1975) Influence of molecular structure on the tolerogenicity of bacterial dextrans. 3. Dissociation between tolerance and immunity to the α1→6 and α1→3 linked epitopes of dextran B1355. Immunology 29:611–619

    PubMed  CAS  Google Scholar 

  • Howard JG, Moreno C, Hale C, Vicari G (1977) Influence of molecular structure on the tolerogenicity of bacterial dextrans. IV. Epitope size recognition and genetic resistance to α1→3 glucosyl tolerance induction by dextran B1355. Eur J Immunol 7:431–436

    Article  PubMed  CAS  Google Scholar 

  • Kabat EA (1961) Experimental Immunochemistry, Charles C. Thomas, Springfield, Illinois, p 241

    Google Scholar 

  • Lukic ML, Cowing C, Leskowitz S (1975) Strain differences in ease of tolerance induction to bovine γ-globulin: dependence on macrophage function. J Immunol 114:503–506

    PubMed  CAS  Google Scholar 

  • Vicari G, Courtenay BM (1977) Restricted avidity of the IgM antibody response to dextran B512 in mice: studies on inhibition of specific plaque forming cells by oligosaccharides. Immunochemistry 14:253–258

    Article  PubMed  CAS  Google Scholar 

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© 1985 Springer-Verlag Berlin Heidelberg

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Howard, J.G. (1985). Immunological Tolerance in BALB/c Mice. In: Potter, M. (eds) The BALB/c Mouse. Current Topics in Microbiology and Immunology, vol 122. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70740-7_25

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  • DOI: https://doi.org/10.1007/978-3-642-70740-7_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70742-1

  • Online ISBN: 978-3-642-70740-7

  • eBook Packages: Springer Book Archive

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