Susceptibility to Abelson or Moloney Murine Leukemia Viruses

  • R. Risser
  • D. Kaehler
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 122)


The differential susceptibilities of inbred mice to tumor development have provided systems to study some of the host cell genes that control these complex processes. In the case of genes that control susceptibility to exogenous tumor viruses several levels of host susceptibility are possible. These include infection of appropriate tissues, transformation of susceptible tissues, and immunological responses to infected or transformed cells. Although there is evidence that each may be the basis of action for some host susceptibility genes; in no case is there sufficient evidence for molecular models of how host susceptibility genes work.


Murine Leukemia Virus Tumor Induction Recombinant Inbred Strain Helper Virus Host Cell Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • R. Risser
  • D. Kaehler

There are no affiliations available

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