The BALB/c Mouse as a Model to Study Orthopoxviruses

  • R. M. L. Buller
Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 122)


The interaction of inbred mice such as the BALB/c group of strains with an infectious agent constitutes a system in which one can study either the pathogenesis of the agent or the host defense mechanisms operative during the disease process. Infection of the BALB/c mouse with poxviruses is such a model system.


Vaccinia Virus Thymidine Kinase Smallpox Vaccination Ectromelia Virus Vaccinia Virus Infection 
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© Springer-Verlag Berlin Heidelberg 1985

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  • R. M. L. Buller

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