Biomechanical Compensatory Mechanisms for Age-Related Changes in Cortical Bone
Age changes in bone mineral mass, volume and density in the human skeleton have been the subject of intensive investigation over the past 25 years. Changes with age in the histologic and mechanical properties of bone have also been studied by many investigators. The general picture emerging from these studies is a progressive net loss of bone mass with aging, beginning in the fifth decade and proceeding at a faster rate among women. Concurrent with this overall loss of bone is the change in bone material properties (Burstein et al, 1976), resulting in a bone tissue of reduced strength and modulus as described above. The major clinical consequence of these skeletal changes is an age-related increase in fracture incidence.
KeywordsCortical Area Bone Mineral Content Bone Width Cortical Bone Area Bone Mineral Mass
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