Skip to main content

Osteogenesis Imperfecta: Current Concepts

  • Conference paper
Current Concepts of Bone Fragility
  • 104 Accesses

Abstract

Exceptional progress in the understanding of osteogenesis imperfecta (OI) during the past decade is due to improved methods for the characterization of procollagens and collagen alpha chains, and the remarkable progress achieved in the molecular biology of collagen genes (Prockop and Vivirikko, 1984). These found ready application in the study of OI and other heritable disorders of connective itssue.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Albright, J.A.: Systemic treatment of osteogenesis imperfecta. Clin. Orthop. Rel. Res. 159, 88, 1981.

    Google Scholar 

  2. Bauze, R.J., Smith, R., and Francis, M.J.O.: A new look at osteogenesis imperfecta. J. Bone Joint Surg. 57B, 2, 1975.

    CAS  Google Scholar 

  3. Binder, H., Hawks, L., Graybill, G., Gerber, N.L., and Weintraub, J.C.: Osteogenesis imperfectaRehabilitation approach with infants and young children. Arch. Phys. Med. Rehabil. 65, 53 7, 1984.

    Google Scholar 

  4. Bleck, E.E.: Nonoperative treatment of osteogenesis imperfecta: Orthotic and mobility management. Clin. Orthop. Rel. Res. 159, 111, 1981.

    Google Scholar 

  5. Bullough, P.G., Davidson, D.D., and Lorenzo, J.C.: The morbid anatomy of the skeleton in osteogenesis imperfecta. Clin. Orthop. Rel. Res. 159, 42, 1981.

    Google Scholar 

  6. Byers, P.H. and Bonadio, J.F.: The molecular basis of clinical heterogeneity in osteogenesis imperfecta: Mutations in Type I collagen genes have different effects on collagen production. In press, 1985.

    Google Scholar 

  7. Hortop, J., Tsipouras, P., Marón, B., and Shapiro, J.R.: Echocardiography findings in osteogenesis imperfecta. In press, 1985.

    Google Scholar 

  8. Prokop, D.J. and Kivirikko, K.I.: Heritable diseases of collagen. New Engl. J. Med. 311, 376, 1984.

    Article  Google Scholar 

  9. Roberts, J.: Bilateral hyperplastic callus formation in osteogenesis imperfecta. J. Bone Joint Surg. 58A, 1164, 1976.

    PubMed  CAS  Google Scholar 

  10. Root, L.: The treatment of osteogenesis imperfecta. Orthop. Clin. North Am. 15, 775, 1984.

    PubMed  CAS  Google Scholar 

  11. Shapiro, J.R. and Rowe, D.W.: Collagen genes and brittle bones. Ann. Int. Med. 99, 711, 1983.

    Google Scholar 

  12. Shapiro, J.R., Bereu, B., and Levine, J.: Thyroid function in osteogenesis imperfecta. In press, 1985.

    Google Scholar 

  13. Sillence, D.O., Senn, A.S., and Danks, D.M.: Genetic heterogeneity in osteogenesis imperfecta. J. Med. Genetics 16, 111, 1979.

    Article  Google Scholar 

  14. Smars, G.: Osteogenesis Imperfecta in Sweden. Svenska Bokforlaget, Stockholm, 1961. p. 69.

    Google Scholar 

  15. Smith, R., Francis, M.J.O., and Houghton, G.R.: The Brittle Bone Syndrome: Osteogenesis Imperfecta. Butterworths, London, 1983.

    Google Scholar 

  16. Weil, U.H.: Osteogenesis imperfecta: Historical background. Clin. Orthop. Rel. Res. 159, 6, 1981.

    Google Scholar 

  17. White, N.J., Wineris, C.B., and Smith, R.: Cardiovascular abnormalities in osteogenesis imperfecta. Am. Heart J. 116, 1416, 1983.

    Article  Google Scholar 

  18. Wynne-Davies, R. and Gormely, J.: Clinical and genetic patterns in osteogenesis imperfecta. Clin. Orthop. Rel. Res. 159, 26, 1981.

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1986 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Shapiro, J.R., Rowe, D.W. (1986). Osteogenesis Imperfecta: Current Concepts. In: Uhthoff, H.K. (eds) Current Concepts of Bone Fragility. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70709-4_18

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-70709-4_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70711-7

  • Online ISBN: 978-3-642-70709-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics