Abstract
The purpose of this report is to describe the histomorphology of the chorion and its possible relationship to mitotic activity of villi. Characterization of the chorion is necessary because of the recent development of first trimester fetal diagnosis by chorionic villi sampling (CVS). A detailed understanding of the cellular composition, function, and behavior of the chorion may materially enhance the quality of cytogenetic analyses performed on villi obtained between 9 and 11 weeks’ gestation. The possibility has been raised that the chorion frondosum may not be morphologically homogeneous. As a consequence, different portions of it may be best suited to different types of chromsomal analysis (e.g., direct preparations as opposed to those obtained from short-them tissue cultures).
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References
Bennington JL (ed) (1978) The development and structure of the placenta. In: Pathology of the placenta. Saunders, London, pp 1–37 (Major problems in pathology, vol 8)
Bergstrom S (1971) Surface ultrastructures of human amnion and chorion in early pregnancy, a scanning electron microscopic study. Obstet Gynecol 38: 513–524
Boyd JD, Hamilton WJ (1970) The human placenta. Heffer, Cambridge
Ciblis LA (1968) Growth of the placenta villi in the first trimester. J Reprod Med 1: 377–387
Demsey EW, Luse SA (1971) Regional specializations in the syncytial trophoblast of early human placentas. J Anat 108: 545–561
Ginsberg N, Brand T, Cadkin A, Verlinsky Y, Pergament E (1985) Technical aspects of chorionic villi sampling in first trimester fetal diagnosis. Hum Genet
King BF, Menton DN (1975) Scanning electron microscopy of human placental villi from early and late gestation. Am J Obstet Gynecol 122: 824–828
Mukai K, Rosai J (1980) Application of immunoperoxidase technique in surgical pathology. In: Fenoglio CM, Wolf M (eds) Progress in surgical pathology, vol 1. Masson, New York, pp 15–49
Sternberger LA (1979) Immunocytochemistry, 2nd edn Wiley, New York
Terzakis JA (1963) The ultrastructure of normal human first trimester placenta. J Ultrastruct Res 9: 268–284
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© 1985 Springer-Verlag Berlin Heidelberg
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Verlinsky, Y., DeChristopher, P.J., Pergament, E., Ginsberg, N.A. (1985). Histomorphological Aspects of Chorionic Villi in First Trimester Fetal Diagnosis. In: Fraccaro, M., Simoni, G., Brambati, B. (eds) First Trimester Fetal Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70707-0_27
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DOI: https://doi.org/10.1007/978-3-642-70707-0_27
Publisher Name: Springer, Berlin, Heidelberg
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