Culturing Trophoblast Samples

  • D. V. Coleman


Chorionic villi sampling (CVS) is now offered as an alternative to amniocentesis in many obstetric units in Europe and the United States for the prenatal diagnosis of fetal abnormality in pregnancies where the risk of genetic disease is high. A major advantage of this technique is that fresh villous material can be used for diagnosis (Williamson et al. 1981; Kazy et al. 1982; Old et al. 1982; Simoni et al. 1983), so that, if termination is indicated, it can be carried out in the first trimester at a time when abortion is safer and less distressing for the mother and more acceptable to the clinic staff involved in her antenatal care.


Amniotic Membrane Chorionic Villus Maternal Cell Trimester Pregnancy Amniotic Fluid Cell 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • D. V. Coleman
    • 1
  1. 1.Dept. of Pathology PaddingtonCytogenetics Unit, St. Mary’s Hospital Medical SchoolLondonUK

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