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First Trimester Fetal Diagnosis pp 74–77Cite as

Fetoplacental Products as a Prognostic Guide Following Chorionic Villi Sampling

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Abstract

The safety of chorionic villi sampling (CVS) as a clinical procedure in fetal diagnosis has yet to be fully assessed. Complications occurring immediately and several weeks after this procedure have been described, but it is still unclear to what extent the complication rate is related to the surgical aspect of the sampling. As some biochemical tests of placental function have been reported as helpful in the prediction of pregnancy outcome following vaginal bleeding, (Westergaard et al. 1983,1985), we have examined proteins of fetal (α-fetoprotein, AFP) and placental (human chorionic gonadotropin, HCG; pregnancy-specific Bi glycoprotein, SPI; and pregnancy-associated protein-A, PAPP-A) origin before and within 6 h of CVS.

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References

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Author information

Authors and Affiliations

  1. Department of Obstetric and Gynecology, University College, 88-96 Chenies Mews, London, WCIE GHX, Great Britain

    R. H. T. Ward, B. Modell, S. Kanakpongsukdi & M. Petrou

  2. Joint Academic Unit of Obstetrics and Gynaecology and Reproductive Physiology, St. Bartholomew’s Hospital Medical School and The London Hospital Medical School, London, UK

    J. G. Grudzinskas & T. Chard

  3. Department of Biochemistry, North East London Polytechnic, London, UK

    A. E. Bolton

Authors
  1. R. H. T. Ward
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  2. J. G. Grudzinskas
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  3. A. E. Bolton
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  4. B. Modell
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  5. S. Kanakpongsukdi
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  6. M. Petrou
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  7. T. Chard
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Editor information

Editors and Affiliations

  1. Istituto di Biologia Generale e Genetica Medica, Via Forlanini 14, C.P. 217, I-27100, Pavia, Italy

    Marco Fraccaro

  2. Laboratorio di Citogenetica, I. Clinica Ostetrica e Ginecologica, Universitá di Milano, Via Commenda 12, I-20122, Milano, Italy

    Giuseppe Simoni

  3. Unità di Medicina Perinatale, I. Clinica Ostetrica e Ginecologica, Università di Milano, Via Commenda 12, I-20122, Milano, Italy

    Bruno Brambati M.D.

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© 1985 Springer-Verlag Berlin Heidelberg

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Ward, R.H.T. et al. (1985). Fetoplacental Products as a Prognostic Guide Following Chorionic Villi Sampling. In: Fraccaro, M., Simoni, G., Brambati, B. (eds) First Trimester Fetal Diagnosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70707-0_14

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  • DOI: https://doi.org/10.1007/978-3-642-70707-0_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15785-4

  • Online ISBN: 978-3-642-70707-0

  • eBook Packages: Springer Book Archive

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