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Fetoplacental Products as a Prognostic Guide Following Chorionic Villi Sampling

  • R. H. T. Ward
  • J. G. Grudzinskas
  • A. E. Bolton
  • B. Modell
  • S. Kanakpongsukdi
  • M. Petrou
  • T. Chard

Abstract

The safety of chorionic villi sampling (CVS) as a clinical procedure in fetal diagnosis has yet to be fully assessed. Complications occurring immediately and several weeks after this procedure have been described, but it is still unclear to what extent the complication rate is related to the surgical aspect of the sampling. As some biochemical tests of placental function have been reported as helpful in the prediction of pregnancy outcome following vaginal bleeding, (Westergaard et al. 1983,1985), we have examined proteins of fetal (α-fetoprotein, AFP) and placental (human chorionic gonadotropin, HCG; pregnancy-specific Bi glycoprotein, SPI; and pregnancy-associated protein-A, PAPP-A) origin before and within 6 h of CVS.

Keywords

Spontaneous Abortion Hospital Medical School Chorionic Villus Sampling Chorionic Villus Sampling Fetal Diagnosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • R. H. T. Ward
    • 1
  • J. G. Grudzinskas
    • 2
  • A. E. Bolton
    • 3
  • B. Modell
    • 1
  • S. Kanakpongsukdi
    • 1
  • M. Petrou
    • 1
  • T. Chard
    • 2
  1. 1.Department of Obstetric and GynecologyUniversity CollegeLondonGreat Britain
  2. 2.Joint Academic Unit of Obstetrics and Gynaecology and Reproductive PhysiologySt. Bartholomew’s Hospital Medical School and The London Hospital Medical SchoolLondonUK
  3. 3.Department of BiochemistryNorth East London PolytechnicLondonUK

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