Effect of CSF Albumin Concentration on NMR Relaxation Parameters
Imaging with nuclear magnetic resonance (NMR) is a sensitive indicator of the location and extent of brain edema [1, 2]. Indeed, preliminary studies indicate that NMR imaging gives better definition of the extent and mass effects of edema than is achievable at present with X-ray computed tomography (CT) [1, 3]. CT gives information only on tissue density (i.e., the coefficient of linear X-ray absorption), whereas proton NMR provides information related to the density of mobile hydrogen and to its relaxation behavior; i.e., the longitudinal (T1) and transverse (T2) relaxation times. The corresponding relaxation rates are given as 1/T1 and 1/T2.
Key wordsNuclear magnetic resonance brain edema proton-relaxation cerebrospinal fluid albumin
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