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Effect of CSF Albumin Concentration on NMR Relaxation Parameters

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Brain Edema
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Abstract

Imaging with nuclear magnetic resonance (NMR) is a sensitive indicator of the location and extent of brain edema [1, 2]. Indeed, preliminary studies indicate that NMR imaging gives better definition of the extent and mass effects of edema than is achievable at present with X-ray computed tomography (CT) [1, 3]. CT gives information only on tissue density (i.e., the coefficient of linear X-ray absorption), whereas proton NMR provides information related to the density of mobile hydrogen and to its relaxation behavior; i.e., the longitudinal (T1) and transverse (T2) relaxation times. The corresponding relaxation rates are given as 1/T1 and 1/T2.

The study described in this paper was supported by grants from the Alberta Heritage Foundation for Medical Research (major equipment) and the Alberta Heritage Savings Trust Fund for Applied Research — Cancer (H-184: H-340). MEC is an Alberta Heritage Foundation for Medical Research Fellow.

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© 1985 Springer-Verlag Berlin Heidelberg

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Castro, M.E., Boisvert, D.P., Treiber, E.O., Lunt, J.A., Allen, P.S. (1985). Effect of CSF Albumin Concentration on NMR Relaxation Parameters. In: Inaba, Y., Klatzo, I., Spatz, M. (eds) Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70696-7_90

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  • DOI: https://doi.org/10.1007/978-3-642-70696-7_90

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70698-1

  • Online ISBN: 978-3-642-70696-7

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