Effect of a Calcium Antagonist, Nicardipine, on Ischemic Brain Edema Formation
The effects of calcium antagonists on cerebral ischemia or anoxia have been widely discussed [1, 2]. But there is some controversy about their beneficial effects. We studied the influence of a calcium antagonist , nicardipine, on the cortical blood flow (1CBF) and specific gravity (SG) following focal cerebral ischemia.
Key wordsCalcium antagonist nicardipine cerebral blood flow hydrogen clearance specific gravity
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- 1.Kazda S, Garthoff B, Krause HP, Schlossmann K (1982) Cerebrovascular effect of the calcium antagonistic dihydropyridine derivative nimodipine in animal experiments. Drug Res 32:331–338Google Scholar