Abstract
In head-injury patients, vasogenic edema results from damage to cerebral cortical vessels, which permits the extravasation of plasma ultrafiltrate into the surrounding extracellular space. Although the electrophysiological effects of white matter edema have been studied [3, 6, 8], it remains unclear whether the exudation of plasma into the cerebral cortex results in any direct impairment of cortical function. The present experiment was carried out to study the effects of cortical edema and ischemia on cortical neural activity. The air-exposure edema used does not induce direct cortical injury comparable to that caused by cold injury or brain compression. Effects of a high dose of steroid on cortical neural function were also investigated.
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Abbreviations
- ICBF:
-
local cortical blood flow
- DCR:
-
direct cortical response
- MP:
-
methylprednisolone
- BBB:
-
blood brain barrier
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© 1985 Springer-Verlag Berlin Heidelberg
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Nagao, S. et al. (1985). Vasogenic Brain Edema and Cortical Neural Function. In: Inaba, Y., Klatzo, I., Spatz, M. (eds) Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70696-7_38
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DOI: https://doi.org/10.1007/978-3-642-70696-7_38
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70698-1
Online ISBN: 978-3-642-70696-7
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