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Brain Edema pp 165-169 | Cite as

Cell Volume Regulation of Glial Cells During Anoxia and Hyposmotic Exposure In Vitro

  • O. Kempski
  • M. Zimmer
  • A. Neu
  • F. von Rosen
  • A. Baethmann
Conference paper

Abstract

The swelling of dendrites and glial cells is a morphologically significant feature of cytotoxic brain edema, which is regularly observed in cerebral ischemia. Cellular hydrops is usually explained by a disturbed double Donnan equilibrium [10], and it is thought to be an immediate result of failing ion pumps in the presence of a reduced supply of metabolic energy.

Key words

Cytotoxic brain edema anoxia cell volume regulation glia membrane permeability 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • O. Kempski
    • 1
    • 2
  • M. Zimmer
  • A. Neu
  • F. von Rosen
  • A. Baethmann
  1. 1.Institute for Surgical ResearchLudwig-Maximilians UniversityMunichGermany
  2. 2.Klinikum GroßhadernMunich 70Germany

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