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Brain Edema pp 149–154Cite as

Early Permeability Change of Macromolecules After Transient Global Ischemia

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Abstract

Vascular permeability to macromolecular tracers is known to increase in various types of brain damage [1, 3, 4]. In transient ischemia with hypoxia, extravasation of Evans blue-albumin complex (EB) and horseradish peroxidase (HRP) may take place by different mechanisms [1]. The early changes in vascular permeability to HRP and EB were studied by electron and fluorescence microscopy in rats subjected to three-vessel occlusion.

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References

  1. Petito CK (1979) Early and late mechanisms of increased vascular permeability following experimental cerebral infarction. J Neuropathol Exp Neurol 38:222–234

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  2. Lossinsky AS, Garcia JH, Iwanowski L, Lightfoot WE Jr. (1979) New ultrastructural evidence for a protein transport system in endothelial cells of gerbil brains. Acta Neuropathol 47:105–110

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  4. Hossmann KA, Olsson Y (1971) The effect of transient cerebral ischemia on the vascular permeability to protein tracers. Acta Neuropathol 18:103–112

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© 1985 Springer-Verlag Berlin Heidelberg

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Arai, H., Suzuki, M., Suzuki, J., Iwasaki, Y. (1985). Early Permeability Change of Macromolecules After Transient Global Ischemia. In: Inaba, Y., Klatzo, I., Spatz, M. (eds) Brain Edema. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70696-7_21

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  • DOI: https://doi.org/10.1007/978-3-642-70696-7_21

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70698-1

  • Online ISBN: 978-3-642-70696-7

  • eBook Packages: Springer Book Archive

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