Abstract
The mammalian cerebral cortex is characterized by a radial organization which derives from the radial neuronal architectonics of the embryonic cortical plate. This normal cell pattern of the embryonic cortex is necessary for the development of cortical lamination and foliation as well as columnar organization. The purpose of this work is to show that radial organization of the embryonic cortical plate is: (1) the result of a progressive build-up during brain evolution and (2) under genetic control, particularly from the reeler locus (in mice).
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References
Caviness VS Jr (1982) Neocortieal histogenesis in normal and reeler mice: a developmental study based upon H-3-Thymidine autoradiography. Dev Brain Res 4: 293–302
Caviness VS Jr, Rakic P (1978) Mechanisms of cortical development: a view from mutations in mice. Annu Rev Neurosci 1: 297–326
Edelman GM (1984) Modulation of cell adhesion during induction, histogenesis and perinatal development of the nervous system. Annu Rev Neurosci 7: 339–378
Goffinet AM (1983) The embryonic development of the cortical plate in reptiles. J Comp Neurol 215: 437–452
Goffinet AM (1984a) Phylogenetic determinants of radial organization in the cerebral cortex. Z Mikrosk-Anat Forsch 98: 909–925
Goffinet AM (1984b) Events governing organization of postmigratory neurons: studies on brain development in normal and reeler mice. Brain Res Rev 7: 261–296
Goffinet AM, Daumerie Ch, Langerwerf B, Pieau C (1985) Neurogenesis in the reptile cortex: H-3-Thymidine autoradiographci analysis. Soc Neurosci Abstr (in press)
Northcutt RG (1981) Evolution of the telencephalon in non mammals. Annu Rev Neurosci 4: 301–350
Pinto-Lord MC, Evrard Ph, Caviness VS Jr (1982) Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: a Golgi-EM analysis. Dev Brain Res 4: 379–393
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© 1986 Springer-Verlag Berlin Heidelberg
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Goffinet, A., Daumerie, C. (1986). Radial Organization of the Cerebral Cortex: Genetic and Phylogenetic Determinants. In: Montalcini, R.L., Calissano, P., Kandel, E.R., Maggi, A. (eds) Molecular Aspects of Neurobiology. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70690-5_27
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DOI: https://doi.org/10.1007/978-3-642-70690-5_27
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70692-9
Online ISBN: 978-3-642-70690-5
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