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On the Hydrophobic Interaction of Neuromuscular Blocking Agents with Acetylcholine Receptors of Skeletal Muscles

  • Chapter
New Neuromuscular Blocking Agents

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 79))

Abstract

One of the most important tasks of the pharmacology of neuromuscular transmission is to determine the principles of interaction of neuromuscular blocking agents with acetylcholine receptors of skeletal muscles. Such studies can be important for the specification of the structure of nicotinic receptors of the end-plate and for the purposeful synthesis of new neuromuscular blocking agents (Cavallito and Gray 1960; Stenlake 1963; Barlow 1968; Kharkevich 1969, 1970c, 1973, 1974, 1975, 1983; Kharkevich and Skoldinov 1970, 1971, 1974, 1976, 1980; Kier 1971; Triggle et al. 1971; Anichkov 1974; Albert 1979; Cavallito 1980, etc.).

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Authors
  1. D. A. Kharkevich
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  2. A. P. Skoldinov
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Editor information

Editors and Affiliations

  1. Department of Pharmacology, Academy of Medical Sciences First Medical Institute, 2/6 Pirogovskaya Street, Moscow, II9435, USSR

    Dimitry A. Kharkevich M.D., D. Sc. (Professor and Chairman of the Department of Pharmacology Academician of the USSR) (Professor and Chairman of the Department of Pharmacology Academician of the USSR)

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© 1986 Springer-Verlag Berlin Heidelberg

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Kharkevich, D.A., Skoldinov, A.P. (1986). On the Hydrophobic Interaction of Neuromuscular Blocking Agents with Acetylcholine Receptors of Skeletal Muscles. In: Kharkevich, D.A. (eds) New Neuromuscular Blocking Agents. Handbook of Experimental Pharmacology, vol 79. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70682-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-70682-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70684-4

  • Online ISBN: 978-3-642-70682-0

  • eBook Packages: Springer Book Archive

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