Delphinium Alkaloids

  • M. D. Mashkovsky
  • V. V. Churyukanov
Part of the Handbook of Experimental Pharmacology book series (HEP, volume 79)


Delphinium plants of the family Ranunculaceae are widely spread over the world. Some of the plants belonging to this genus grow in central Asia and other regions of the USSR. These plants are known to be poisonous; animals eating them show the effects of poisoning, the symptoms of muscle relaxation being predominant. As far back as the beginning of the nineteenth century, a crystalline base called delphinine (C34H47O9N) was isolated from Delphinium staphisagria L. Later on, a number of alkaloids were obtained from different types of delphinium. All of them are tertiary bases.


Neuromuscular Blocking Anthranilic Acid Neuromuscular Transmission Nictitate Membrane Neuromuscular Blocking Agent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Chlenov LC, Serkova MP (1957) Drug treatment of spastic hemipareses (in Russian). Klin Med 35:32–37Google Scholar
  2. Dozortseva PM (1956) On the pharmacology of alkaloids from Delfinium elatum (elati-num and eldelinum) (in Russian). Farmakol Toksikol 3:42–48Google Scholar
  3. Dozortseva PM (1958) Mellictinum is the new drug for treatment of spastic pareses (in Russian). Med Tekh 11:54Google Scholar
  4. Dozortseva PM (1959) The pharmacology of alkaloid methyllicaconitine (mellictine) (in Russian). Farmakol Toksikol 1:34–38Google Scholar
  5. Dozortseva PM, Mashkovsky MD (1951) On the comparative pharmacology of alkaloids delsemine and delsin (in Russian). Farmakol Toksikol 4:49–54Google Scholar
  6. Kobelyanskaya LG (1959) Administration of mellictine in a neurological clinic in spastic pareses (in Russian). Farmakol Toksikol 1:38–42Google Scholar
  7. Kuzovkov AD, Bocharnikova AV (1958) Research of aconite alkaloids. X. Elatin. The structure of esterifying acid (in Russian). Zh Obshch Khim 28:556–558Google Scholar
  8. Kuzovkov AD, Platonova TF (1959) The study of aconite alkaloids. XV. On the structure of elatinum, methyllicaconitine, ajacine, delseminum, avadkharidine, licaconitine, and eldelinum (in Russian) Zh Obshch Khim 29:2782–2786Google Scholar
  9. Kuzovkov AD, Platonova TF (1962) Research of aconite alkaloids. XIX. On the structure of eldelin and delfelin (in Russian). Zh Obshch Khim 32:1290–1293Google Scholar
  10. Mashkovsky MD (1943) On the pharmacology of alkaloid thesin (in Russian). Farmakol Toksikol 1:25–32Google Scholar
  11. Orekhov AP (1955) Chimia alkaloidow (Chemistry of alkaloids) Academy of Sciences, MoscowGoogle Scholar
  12. Pelletier SW, Bhattacharyya G (1977) The nature of “delsemine” from Delphinium semi-barbatum (Dwarf Larkspur). Tetrahedron Lett 32:2735–2736CrossRefGoogle Scholar
  13. Pelletier SW, Keith IH, Parthasarathy PS (1967) The structures of condelphine, isotala-tizidine and talatizidine. J Am Chem Soc 89:4146–4157PubMedCrossRefGoogle Scholar
  14. Serkova MP (1956) Application of elatin in neurological clinic for spastic pareses treatment (in Russian). Farmakol Toksikol 3:48–51Google Scholar
  15. Yunusov SY (1981) Alkaloidy (Alkaloids) Fun, TashkentGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • M. D. Mashkovsky
  • V. V. Churyukanov

There are no affiliations available

Personalised recommendations