Abstract
Quinuclidine (I) is a bicyclic compound with a tertiary bridgehead nitrogen atom. As regards the chemical structure, it is similar to quinolizidine (norlupinane) (II), pyrrolizidine (III), and to some other 1-azabicyclic compounds which have given rise to numerous pharmacologically active alkaloids and synthetic compounds. Quinuclidine might also be regarded as a closed bicyclic analog of the dialkylami-noalkanes (IV) and N-methylpiperidine (V). The dialkylaminoalkane and N-methylpiperidine group occur in numerous neurotropic and other pharmacologically active compounds.
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© 1986 Springer-Verlag Berlin Heidelberg
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Mashkovsky, M.D., Yakhontov, L.N., Churyukanov, V.V. (1986). Quinuclidinium Compounds. In: Kharkevich, D.A. (eds) New Neuromuscular Blocking Agents. Handbook of Experimental Pharmacology, vol 79. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70682-0_14
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DOI: https://doi.org/10.1007/978-3-642-70682-0_14
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