Abstract
The EEG in normal adults is characterized by an occipitally dominant 10-Hz alpha rhythm (Fig. 1). The alpha rhythm is reactive, meaning it is attenuated when the eyes are open (Fig. 2) and reappears after eye closure. Even centenarians may have an EEG with a normal alpha rhythm. However, Busse et al. (1956) found that 51% of normal subjects over 60 years of age showed slight EEG abnormalities, mainly focal, in the anterior-temporal regions. The percentage of focal abnormalities increases with age from about 20% in the 40–59-year-old to about 30%–40% in the 60–79-year-old group (Busse and Obrist 1965). These findings have been confirmed by several other authors. The proportion of focal changes in normal aged subjects should not exceed 25% of the EEG record.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abbott J (1959) The EEG in Jakob-Creutzfeldt’s disease. Electroencephalogr Clin Neurophysiol 11: 184–185
Andermann K, Stoller A (1961) EEG patterns in hospitalized and non-hospitalized aged. Electroencephalogr Clin Neurophysiol 13: 319
Berger H (1933) Ober das Elektrencephalogramm des Menschen V. Arch Psychiatr Nervenkr 98: 231–254
Brun A, Gustafson L (1978) Limbic lobe involvement in presenile dementia. Arch Psychiatr Nervenkr 226: 79–93
Busse EW, Obrist WD (1965) Pre-senescent electroencephalographic changes in normal subjects. J Gerontol 20: 315–320
Busse EW, Barnes RH, Friedman EL, Kelty EJ (1956) Aged individuals with normal and abnormal electroencephalograms. J Nery Ment Dis 124: 135–141
Cahan RB, Yeager CL (1966) Admission EEG as a predictor of mortality and discharge for aged hospital patients. J Gerontol 21: 248–256
Coben LA, Danziger WL, Berg L (1983 a) Frequency analysis of the resting awake EEG in mild senile dementia of Alzheimer type. Electroencephalogr Clin Neurophysiol 55: 372–380
Coben LA, Danziger WL, Hughes CP (1983 b) Visual evoked potentials in mild senile dementia of Alzheimer type. Electroencephalogr Clin Neurophysiol 55: 121–130
Cosi V, Vitelli E, Gozzoli L, Corona A, Ceroni M, Callieco R (1982) Visual evoked potentials in aging of the brain. In: Courjon J, Mauguière F, Revol M (eds) Clinical applications of evoked potentials in neurology. Raven, New York, pp 109–115
Dejaiffe G, Constantinidis J, Rey-Bellet J, Tissot R (1964) Corrélations électrocliniques dans les démences de l’âge avancé. Acta Neurol Belg 64: 677–707
Drachman DA, Hughes JR (1971) Memory and the hippocampal complexes. III Aging and temporal EEG abnormalities. Neurology (Minneapolis) 21: 1–14
England AC, Schwab RS, Peterson E (1959) The electroencephalogram in Parkinson’s syndrome. Electroencephalogr Clin Neurophysiol 11: 723–731
Friedland RP, Budinger TF, Ganz E, Yano Y, Mathis CA, Koss B, Ober BA, Huesman RH, Derenzo SE (1983) Regional cerebral metabolic alterations in dementia of the Alzheimer type: positron emission tomography with [18F]fluorodeoxyglucose. J Comput Assist Tomogr 7: 590–598
Gibbs FA, Gibbs EL (1951) Changes with age, awake. In: Gibbs FA, Gibbs EL (eds) Atlas of electroencephalography, vol I. Methodology and methods. Addison-Wesley, Reading (Mass), pp 82–88
Gloor P, Kalabay O, Giard N (1968) The electroencephalogram in diffuse encephalopathies.
Electroencephalographic correlates of grey and white matter lesions. Brain 91:779–802
Gordon EB, Sim M (1967) The EEG in presenile dementia. J Neurol Neurosurg Psychiatr 30: 285–291
Greenblatt M, Levin S, Atwell C (1945) Comparative value of electroencephalogram and abstraction tests in diagnosis of brain damage. J Nery Ment Dis 102: 383–391
Gustafson L, Risberg J, Hagberg B, Hoigaard K, Nilssen L, Ingvar DH (1972) Cerebral blood flow, EEG and psychometric variables related to clinical findings in presenile dementia. Acta Neurol Scand [Suppl] 51: 439–440
Hendrickson E, Levy R, Post F (1979) Averaged evoked responses in relation to cognitive and affective state of elderly psychiatric patients. Br J Psychiatry 134: 494–501
Huisman UW, Posthuma J, Hooijer V, Visser SL, De Rijke W (1985) Somatosensory evoked po-tentials in healthy volunteers and patients with dementia. Clin Neurol Neurosurg 87: 11–16
Ingvar DH, Gustafson L (1970) Regional cerebral blood flow in organic dementia with early on-set. Acta Neurol Scand 46 [Suppl] 43: 42–73
Jones DP, Nevin S (1954) Rapidly progressive cerebral degeneration (subacute vascular encephalopathy) with mental disorder, focal disturbances and myoclonic epilepsy. J Neurol Neurosurg Psychiatr 17: 148–159
Laidlaw J, Catling J (1964) An EEG assessment of encephalopathy in Parkinsonism. J Neurol Neurosurg Psychiatr 27: 232–236
Laurian S, Lobrinus S, Wertheimer J, Gaillard JM (1977) Evoked responses in dementia and the significance of the vertex potential. Electroencephalogr Clin Neurophysiol 43: 525–526
Letemendia F, Pampiglione G (1958) Clinical and EEG observations in Alzheimer’s disease. J Neurol Neurosurg Psychiatr 21: 167–172
Levy E, Isaacs A, Behrman J (1971) Neurophysiological correlates of senile dementia. II The somatosensory evoked response. Psychol Med 1: 159–165
Liddell DW (1958) Investigations of EEG findings in presenile dementia. J Neurol Neurosurg Psychiatr 21: 173–176
Lundervold A, Engeset A, Lonnum A (1962) The EEG in cerebral atrophy. World Neurol 3: 226–234
McAdam W, Robinson RA (1956) Senile intellectual deterioration and the EEG; quantitative correlation. J Ment Sci 102: 819–825
McEvoy TM, Harkins SW (1981) Brainstem auditory evoked potentials in patients with pre-senile dementia. Abstracts XII Intern Congress Gerontology, Hamburg, vol 2, p 218
Mundy-Castle AC, Hurst LA, Beerstecher DM, Prinsloo T (1954) The electroencephalogram in senile psychoses. Electroencephalogr Clin Neurophysiol 6: 245–252
Obrist WD (1954) The electroencephalogram of normal aged adults. Electroencephalogr Clin Neurophysiol 6: 235–244
Obrist WD (1963) The EEG of healthy aged males. In: Birren JE, Butler RN, Greenhouse SW, Sokoloff L, Yarrow MR (eds) Human aging: a biological and behavioral study. US Govt Printing Office, Washington PHS Publ No 986, pp 79–93
Obrist WD, Henry CE (1958) Electroencephalographic frequency analysis of aged psychiatric patients. Electroencephalogr Clin Neurophysiol 10: 621–632
Obrist WD, Busse EW, Eisdorfer C, Kleemeier RE (1962) Relation of the electroencephalogram to intellectual function in senescence. J Gerontol 17: 197–206
Roberts MA, McGeorge AP, Caird FI (1978) EEG and computerized tomography in vascular and non-vascular dementia in old age. J Neurol Neurosurg Psychiatr 41: 903–906
Scott DF, Heathfield KWG, Toone B, Margerison JH (1972) The EEG in Huntington’s chorea: a clinical and neuropathological study. J Neurol Neurosurg Psychiatr 35: 97–102
Sisson BD, Ellingson RJ (1956) The EEG in cerebral atrophy. J Nery Ment Dis 123: 244–248
Soininen H, Partanen VJ, Helkala EL, Riekkinen PJ (1982 a) EEG findings in senile dementia and normal aging. Acta Neurol Scand 65: 59–70
Soininen H, Partanen JV; Puranen M, Riekkinen PJ (1982 b) EEG and computed tomography in the investigation of patients with senile dementia. J Neurol Neurosurg Psychiatry 45: 71 1714
Stoller A (1949) Slowing of the alpha rhythm on the EEG and its association with mental deterioration and epilepsy. J Ment Sci 95: 972–984
Straumanis JJ, Shagass C, Schwartz M (1965) Visually evoked cerebral response changes associated with chronic brain syndromes and aging. J Gerontol 20: 498–506
Visser SL, Stam FC, Van Tilburg W, Op den Velde W, Blom JL, De Rijke W (1976) Visual evoked response in senile and presenile dementia. Electroencephalogr Clin Neurophysiol 40: 385–392
Visser SL, Van Tilburg W, Hooijer C, Jonker C, De Rijke W (1985) Visual evoked potentials (VEPs) in senile dementia ( Alzheimer type) and in non-organic behavioural disorders in the elderly; comparison with EEG parameters. Electroencephalogr Clin Neurophysiol 60: 115121
Vogel F, Wendt GG, Oepen H (1961) Das EEG und das Problem einer Frühdiagnose der Chorea Huntington. Dtsch Z Nervenheilk 182:: 355–361
Weiner H, Schuster DB (1956) The electroencephalogram in dementia — some preliminary observations and correlations. Electroencephalogr Clin Neurophysiol 8: 479–488
Wright CE, Harding GFA, Orwin A (1984) Presenile dementia — the use of the flash and pattern VEP in diagnosis. Electroencephalogr Clin Neurophysiol 57: 405–415
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1985 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Visser, S.L. (1985). EEG and Evoked Potentials in the Diagnosis of Dementias. In: Traber, J., Gispen, W.H. (eds) Senile Dementia of the Alzheimer Type. Advances in Applied Neurological Sciences, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70644-8_8
Download citation
DOI: https://doi.org/10.1007/978-3-642-70644-8_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70646-2
Online ISBN: 978-3-642-70644-8
eBook Packages: Springer Book Archive