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Cognitive Deficits in Parkinson’s Disease

  • Conference paper
Senile Dementia of the Alzheimer Type

Part of the book series: Advances in Applied Neurological Sciences ((NEUROLOGICAL,volume 2))

Abstract

Motor abnormalities dominate the clinical picture of Parkinson’s disease. Bradykinesia, caused by severe damage to the ascending nigrostriatal dopaminergic projection, leads to a slight hesitancy in initiating voluntary acts, a difficulty in performing repetitive movements with a progressive reduction in their amplitude, a poorly defined fatigue and possibly an additional defect of motor intention. Many patients also have an inability to attend to two motor commands simultaneously, and more complex perceptual-motor abnormalities have also been detected. Muscle rigidity, a coarse resting tremor and postural instability compound the patient’s incapacities, all of which are exquisitely influenced by the emotions.

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Author information

Authors and Affiliations

  1. Maida Vale Hospital, The National Hospitals for Nervous Diseases, London, W9 1TL, UK

    A. J. Lees

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  1. A. J. Lees
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Editors and Affiliations

  1. Neurobiology Department, Troponwerke GmbH & Co. KG, Neurather Ring 1, D-5000, Köln 80, Germany

    Jörg Traber

  2. Division of Molecular Neurobiology Rudolf Magnus Institute for Pharmacology and Institute of Molecular Biology, State University of Utrecht, Padualaan 8, NL-3508 TB, Utrecht, The Netherlands

    Willem Hendrik Gispen

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© 1985 Springer-Verlag Berlin Heidelberg

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Lees, A.J. (1985). Cognitive Deficits in Parkinson’s Disease. In: Traber, J., Gispen, W.H. (eds) Senile Dementia of the Alzheimer Type. Advances in Applied Neurological Sciences, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70644-8_5

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  • DOI: https://doi.org/10.1007/978-3-642-70644-8_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70646-2

  • Online ISBN: 978-3-642-70644-8

  • eBook Packages: Springer Book Archive

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