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Immunpathogenese der Pyelonephritis

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Der Harnwegsinfekt

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Zusammenfassung

Fast regelmäßig läßt sich bei der Pyelonephritis eine spezifische Immunantwort gegen den verursachenden Erreger finden. Inwieweit jedoch die Immunantwort Entstehung und Verlauf der Pyelonephritis beeinflußt, ist bisher ungeklärt. In Analogie zu anderen Infektionen könnte angenommen werden, daß eine Verschiebung der Erreger-Wirt-Beziehung zu Gunsten eines virulenten Erregers die Niereninfektion begünstigt. Bei Etablierung der Infektion reagiert der Wirt zunächst mit einem Einstrom von Granulozyten; anschließend herrschen lymphatische Zellen vor, wobei sowohl T-Lymphozyten, die für verzögerte Immunreaktionen verantwortlich sind, als auch B-Lymphozyten und ihre Produkte (Antikörper) lokal nachweisbar sind.

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Authors and Affiliations

  1. Mitglied des Sonderforschungsbereiches 107 Kinderklinik und Kinder-Poliklinik, Klinikum der Johannes-Gutenberg-Universität Mainz, Langenbeckstr. 1, D-6500, Mainz

    H. Schulte-Wissermann & W. Mannhardt

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  1. H. Schulte-Wissermann
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  2. W. Mannhardt
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Editors and Affiliations

  1. Lehrstuhl und Abteilung Für Urologie, Eberhard-Karls Universität Tübingen, Calwer Straße 7, Tübingen, Germany

    Karl-Horst Bichler (Ärztl. Direktor) (Ärztl. Direktor)

  2. Urologischen Abteilung, Bundeswehrkrankenhaus Ulm, D-7900, Oberer Eselsberg 40, Ulm, Germany

    Jens E. Altwein FLA (Leitender Arzt) (Leitender Arzt)

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© 1985 Springer-Verlag Berlin Heidelberg

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Schulte-Wissermann, H., Mannhardt, W. (1985). Immunpathogenese der Pyelonephritis. In: Bichler, KH., Altwein, J.E. (eds) Der Harnwegsinfekt. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70642-4_1

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  • DOI: https://doi.org/10.1007/978-3-642-70642-4_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70643-1

  • Online ISBN: 978-3-642-70642-4

  • eBook Packages: Springer Book Archive

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