Adsorption Properties for PAH of Asbestos and Iron Oxides, in Relation with Their Activity in Biological Medium

  • J. Fournier
  • J. B. Nwa Nangwa
  • J. Guignard
  • H. Pezerat
Part of the NATO ASI Series book series (volume 3)


The aim of this study is to reveal the nature of the physicochemical interactions between some solid particles and polynuclear aromatic hydrocarbon (PAH) in organic medium so as help understand the synergistic effects between PAH and these solids in lung cancers. The mechanism underlying these synergistic effects in largely unknown though some in vitro studies are beginning to provide information for the asbestos PAH association (Lakowicz and Bevan 1980; Chang et al. 1982; Mossman et al. 1983; Eastman et al. 1983).


Iron Oxide Organic Medium Surface Charge Density Polynuclear Aromatic Hydrocarbon Syrian Golden Hamster 
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  1. Anthoine D, Lamy F, De Ren G, Braun P, Cervon P, Petiet G, Schartz P, Zuck P, Lamaze R (1979) Le cancer bronchique des mineurs de fer de Lorraine. Arch Mal Prof 40: 48–51Google Scholar
  2. Bonneau L (1982) Thesis, Université P. et M. Curie, ParisGoogle Scholar
  3. Bonneau L, Suquet H, Pezerat H ( 1984 a) Studies on surfaces properties of asbestos. I. Active sites on surface of chrysotile and amphiboles. Submitted in Environmental ResearchGoogle Scholar
  4. Bonneau L, Zalma R, Guignard J, Pezerat H, Mansuy D, Fontecave M ( 1984 b) Active sites of surface and catalytic properties of asbestos mineral. Possible consequence for their activity in biological medium. Published in this journalGoogle Scholar
  5. Borggaard OK (1983) Effect of surface area and mineralogy of iron oxides on their surface charge and anion-adsorption properties. Clays Clay Miner 31: 230–232CrossRefGoogle Scholar
  6. Cases JM (1979) Adsorption des tensio-actifs à l’interface solide-liquide: thermodynamique et influence de l’hétérogénéité des adsorbants. Bull Miner Soc Fr 102: 684–707Google Scholar
  7. Chang MJW, Singh NP, Turturro A, Hart RW (1982) Interaction of benzo(a)pyrene and chrysotile. In: Polynuclear aromatic hydrocarbons: physical and biological chemistry. Batelle Press, Columbus, Ohio, p161Google Scholar
  8. Chang MJW, Hart RW (1983) The effect of asbestos on the uptake and metabolism of benzo(a)pyrene by normal human fibroblast. In: Seventh international symposium on PAH (in press)Google Scholar
  9. Eastman A, Mossman BT, Bresnick E (1983) Influence of asbestos on the uptake of benzo(a)pyrene and DNA alkylation in hamster tracheal epithelial cells. Cancer Res 43: 1251–1255PubMedGoogle Scholar
  10. Fournier J, Pezerat H (1982) Mode d’adsorption des hydrocarbures polycycliques aromatiques sur les amiantes. Cas du phénanthrêne. J Chem Phys 79: 589–596Google Scholar
  11. Fournier J, Pezerat H (1984) Studies on surface properties of asbestos. I II. Interactions between asbestos and polynuclear aromatic hydrocarbons. Submitted in Environmental ResearchGoogle Scholar
  12. Giles CH (1981) Adsorption at solid/liquid interfaces. Surf Sci 11: 143–171Google Scholar
  13. Lakowicz JR, Bevan DR (1980) Benzo(a)pyrene uptake into rat liver microsomes: effects of adsorption of benzo(a)pyrene to asbestos and non-fibrous mineral particulates. Chem Biol Interact 29: 129–138PubMedCrossRefGoogle Scholar
  14. Mossman BT, Eastman A, Landesman JM, Bresnick E (1983) Effects of crocidolite and chrysotile asbestos on cellular uptake and metabolism of benzo(a)pyrene in hamster tracheal epithelial cells. Env Health Persp 51: 231–333CrossRefGoogle Scholar
  15. Netterheim P (1972) Respiratory carcinogenesis studies with the Syrian golden hamster: a review. Progr exp Tumor Res 16: 185–200Google Scholar
  16. Parfitt RL (1978) Anion adsorption by soils and soil materials. Adv in Agron 30: 1–50CrossRefGoogle Scholar
  17. Pham QT, Gaertner M, Mur JM, Braun P, Gabiano M, Sadoul P (1983) Incidence of lung cancer among iron miners. Eur J Respir Dis 64: 534–540PubMedGoogle Scholar
  18. Saffiotti U (1965) Experimental studies of the conditions of exposure to carcinogens for lung cancer induction. J Air Poll Contr Ass 15: 23–25Google Scholar
  19. Singleton IH, Halsey GD (1954) The solution of Argon in layers of krypton. J Phys Chem 58: 1011–1017CrossRefGoogle Scholar
  20. Thorny A, Duval X (1970) Adsorption de molécules simples sur graphite. II. Variation du potentiel d’adsorption en fonction du nombre de couches adsorbées. J Chim Phy 67: 286–290Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • J. Fournier
    • 1
  • J. B. Nwa Nangwa
    • 1
  • J. Guignard
    • 1
  • H. Pezerat
    • 1
  1. 1.Laboratoire de Chimie des SolidesUniversité P. et M. CurieParis Cedex 05France

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