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Die Wirkung der Benzodiazepine auf neuronaler Ebene

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Benzodiazepine
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Zusammenfassung

Die Suche nach dem neuronalen Wirkungsmechanismus von Psychopharmaka war immer von der Hoffnung getragen, über eine Aufklärung des Wirkungsmechanismus einen Leitfaden in der Hand zu haben, der dann letztlich zu den pathobiochemischen Veränderungen der Erkrangungen führt, die mit der jeweiligen Psychopharmakagruppe behandelbar sind. Im Sinne dieses Konzeptes ist zu hoffen, daß uns durch unser relativ gutes Verständnis des Wirkungsmechanismus der Benzodiazepine ein weiterer Schlüssel in die Hand gegeben ist zum besseren Verständnis neuronaler Grundlagen von Schlaf, Angst, Muskeltonus und Krampfaktivität und deren pathologischer Veränderungen. Ziel der vorliegenden Übersicht soll es daher sein, neben einer kurzen Übersicht über den molekularpharmakologischen Wirkungsmechanismus der Benzodiazepine eine Brücke aufzuzeichnen zwischen diesen neuen Erkenntnissen der Pharmakologie und bereits vorhandenen oder möglichen Ansützen biologisch-psychiatrischer Grundlagenforschung.

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© 1986 Springer-Verlag Berlin Heidelberg

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Müller, W.E. (1986). Die Wirkung der Benzodiazepine auf neuronaler Ebene. In: Hippius, H., Engel, R.R., Laakmann, G. (eds) Benzodiazepine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70621-9_1

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  • DOI: https://doi.org/10.1007/978-3-642-70621-9_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-15634-5

  • Online ISBN: 978-3-642-70621-9

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