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Molecular and Cellular Adaptations of Fish Hemoglobin-Oxygen Affinity to Environmental Changes

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Respiratory Pigments in Animals

Abstract

Comparative biochemists and physiologists have found that the blood-oxygen affinities of various fish species are compatible with the physical and chemical parameters of their environments. For example, fish that live in low oxygen environments have high oxygen affinities while those that live in high oxygen environments have lower oxygen affinities. Moreover, fish that live in environments where physical parameters periodically change, have the necessary molecular machinery required for adaptation. This machinery includes species specific hemoglobins and/or the regulation of various modifier ligands (e. g., organic phosphates, HCO3, CO2, CI, H+, etc.). The intraerythrocyte concentrations of these ligands influence oxygen binding and are directly or indirectly effected by environmental parameters (e. g. temperature). It is, therefore, appropriate to review some aspects of hemoglobin as it relates to these interactions. Once an overview of these linked functions has been established, we shall address some structural and functional aspects of multiple hemoglobins, then turn our attention to the molecular mechanism of adapting to environmental oxygen and temperature to illustrate these phenomena.

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  1. D. A. Powers
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Editors and Affiliations

  1. Laboratory of Biochemistry, University of Francois-Rabelais, 2, Boulevard Tonnellé, F-37032, Tours Cedex, France

    Jean Lamy (Scientific Editor) (Scientific Editor)

  2. Department of Pharmaceutical Science, University of Francois-Rabelais, 2, Boulevard Tonnellé, F-37032, Tours Cedex, France

    Jean Lamy (Scientific Editor) (Scientific Editor)

  3. Laboratory of Neurobiology and Compared Physiology, University of Bordeaux I, Place du Dr. Bertrand Peyneau, F-33120, Arcachon Cedex, France

    Jean-Paul Truchot (Scientific Editor) (Scientific Editor)

  4. Laboratory of Biochemistry, University of Liège, 22, Quai Van Benden, B-4020, Liège, Belgium

    Raymond Gilles (Coordinating Editor) (Coordinating Editor)

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Powers, D.A. (1985). Molecular and Cellular Adaptations of Fish Hemoglobin-Oxygen Affinity to Environmental Changes. In: Lamy, J., Truchot, JP., Gilles, R. (eds) Respiratory Pigments in Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70616-5_8

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  • DOI: https://doi.org/10.1007/978-3-642-70616-5_8

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