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Passive Cl- Currents in Toad Skin: Potential Dependence and Relation to Mitochondria-Rich Cell Density

  • N. J. Willumsen
  • E. Hviid Larsen
Conference paper
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

In tight epithelia, like amphibian skin, the net flow of Cl- ions is predominantly passive and reflects the electrochemical potential gradient across the skin. In the present paper, we shall discuss the dependence of the Cl- current on the transepithelial potential difference. Our hypothesis is that the potential provides not only the driving force for the Cl- flux, but controls the Cl- permeability as well. Evidence is also presented that the passive Cl- pathway is localized to a special cell type, the mitochondria-rich cells. Modes of Cl- permeability regulation, which have been discussed in the literature, are briefly reviewed.

Keywords

Granulosum Cell Current Transient Frog Skin Chloride Transport Bufo Bufo 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1987

Authors and Affiliations

  • N. J. Willumsen
  • E. Hviid Larsen
    • 1
  1. 1.Zoophysiological Laboratory A, August Krogh InstituteUniversity of CopenhagenCopenhagen øDenmark

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