Summary
Seventeen patients with severe posterior uveitis and retinal vasculitis were treated with CyA. An initial improvement occurred in all cases and persisted until the dose was reduced or the drug withdrawn, when a rapid recurrence of symptoms was noted.
Ten patients did not complete the year of therapy, owing to deterioration of renal function (5 cases), severe malaise and nausea (4 cases) and blindness (1 case).
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References
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Nussenblatt RB, Palestine AG, Chan C (1983) Cyclosporin A therapy in the treatment of intraocular inflammatory disease resistant to systemic corticosteroids and cytotoxic agents. Am J Ophthalmol 96:172
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© 1985 Sandoz Ltd, Basle
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Graham, E., Sanders, M.D., Binder, A., Denman, A.M., Dinning, W. (1985). Ciclosporin (CyA) in the Treatment of Retinal Vasculitis. In: Schindler, R. (eds) Ciclosporin in Autoimmune Diseases. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70607-3_21
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DOI: https://doi.org/10.1007/978-3-642-70607-3_21
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-70609-7
Online ISBN: 978-3-642-70607-3
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