Melatonin: A Marker for Tumors of the Pineal Region
In patients with tumors of the pineal region, endocrine abnormalities appear to be more frequent than was previously assumed. It has been suggested that these abnormalities originate in the hypothalamus (1, 3). Melatonin is secreted by the pineal gland and may thus serve as a tumor marker in patients with tumors in this area. Recently, a sensitive radioimmunoassay of melatonin was developed which enabled us to study serum levels of the hormone in patients with pineal tumors. Surprisingly, up to now there have been only single reports on melatonin in neoplastic pineal disease.
KeywordsNeurol Melatonin Craniopharyngiomas
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- 3.Clar, H.E., Andler, W.: Diencephale hormonelle Funktionsstörungen bei Tumoren der Pinealisregion. Verh. Dtsch. Ges. Neurol. I, pp. 447–450. Springer, Berlin Heidelberg New York 1980Google Scholar
- 7.Tharandt, L., Schrenk, C., Rosanowski, F., Kirsch, W., Reinwein, D.: Aufgehobene Melatoninrhythmik bei Akromegalie. Vortrag Dtsch. Ges. Endokrinologie, Heidelberg 1984Google Scholar