Melatonin: A Marker for Tumors of the Pineal Region

  • H.-E. Clar
  • L. Tharandt
  • C. Schrenk
  • F. Rosanowski
  • G. Benker
  • D. Reinwein
Part of the Advances in Neurosurgery book series (NEURO, volume 13)

Abstract

In patients with tumors of the pineal region, endocrine abnormalities appear to be more frequent than was previously assumed. It has been suggested that these abnormalities originate in the hypothalamus (1, 3). Melatonin is secreted by the pineal gland and may thus serve as a tumor marker in patients with tumors in this area. Recently, a sensitive radioimmunoassay of melatonin was developed which enabled us to study serum levels of the hormone in patients with pineal tumors. Surprisingly, up to now there have been only single reports on melatonin in neoplastic pineal disease.

Keywords

Neurol Melatonin Craniopharyngiomas 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • H.-E. Clar
    • 1
  • L. Tharandt
    • 2
  • C. Schrenk
    • 2
  • F. Rosanowski
    • 2
  • G. Benker
    • 2
  • D. Reinwein
    • 2
  1. 1.Abteilung für NeurochirurgieUniversitätsklinikum der Gesamthochschule EssenEssen 1Germany
  2. 2.Medizinische AbteilungUniversitätsklinikum der Gesamthochschule EssenEssen 1Germany

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