Morphology of Vessel Wall Changes After Microsurgical End- to-Side Anastomosis and Their Pharmacological Prevention

  • H. M. Mehdorn
  • S. Hickler
  • K. Venjakob
  • V. Reinhardt
  • W. Grote
Conference paper
Part of the Advances in Neurosurgery book series (NEURO, volume 13)

Abstract

Morphological alterations in the arteries which are involved in extracranial-intracranial (EC/IC) anastomoses may be harmful to EC/IC bypass function. Only a limited number of human specimens of EC/IC anastomoses have been evaluated, by STEINBOK and co-workers (15) and BODOSI and MEREI (3). They described development of arteriosclerotic changes such as interruption of the internal elastic membrane (IEM) and (myo-)intimal hyperplasia (MIH) which, in some instances, led to a marked stenosis of the lumen of the arteries. However, arteriosclerosis occurs frequently in the superficial temporal arteries of EC/IC bypass patients (12), and therefore the finding of arteriosclerosis cannot necessarily be considered as postoperative development.

Keywords

Ischemia Aspirin Neurol Nylon Acetyl 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • H. M. Mehdorn
    • 1
  • S. Hickler
    • 2
  • K. Venjakob
    • 3
  • V. Reinhardt
    • 2
  • W. Grote
    • 1
  1. 1.Abteilung für NeurochirurgieUniversitätsklinikum der Gesamthochschule EssenEssen 1Germany
  2. 2.lnstitut für NeuropathologieUniversitätsklinikum der Gesamthochschule EssenEssen 1Germany
  3. 3.Anatomisches InstitutUniversitätsklinikum der Gesamthochschule EssenEssen 1Germany

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