Morphology of Vessel Wall Changes After Microsurgical End- to-Side Anastomosis and Their Pharmacological Prevention
Morphological alterations in the arteries which are involved in extracranial-intracranial (EC/IC) anastomoses may be harmful to EC/IC bypass function. Only a limited number of human specimens of EC/IC anastomoses have been evaluated, by STEINBOK and co-workers (15) and BODOSI and MEREI (3). They described development of arteriosclerotic changes such as interruption of the internal elastic membrane (IEM) and (myo-)intimal hyperplasia (MIH) which, in some instances, led to a marked stenosis of the lumen of the arteries. However, arteriosclerosis occurs frequently in the superficial temporal arteries of EC/IC bypass patients (12), and therefore the finding of arteriosclerosis cannot necessarily be considered as postoperative development.
KeywordsIntimal Hyperplasia Superficial Temporal Artery Endothelial Denudation Endothelial Hyperplasia Intimal Cell
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