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ADP-Ribosylation as a Cellular Control Mechanism

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ADP-Ribosylation of Proteins

Part of the book series: Proceedings in Life Sciences ((LIFE SCIENCES))

Abstract

It is now about 21 years since the discovery of poly(ADP-ribose). This coming of age is reflected also in the interest and importance of ADP-ribosylation reactions in cell and molecular biology.

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References

  1. Shall S. Durkacz BW, Gray DA, Irwin J, Lewis PJ, Perera M, Tavassoli M (1982) (ADP-ribose)n participates in DNA excision repair. In: Harris CC, Cerutti PA (eds) Mechanisms of chemical carcinogenesis. Liss, New York, pp 389–407

    Google Scholar 

  2. Shall S (1983) ADP-ribosylation, DNA repair, cell differentiation and cancer. In: Miwa M, Hayaishi O, Shall S, Smulson M, Sugimura T (eds) ADP-ribosylation, DNA repair and cancer. Jpn Sci Soc Press, Tokyo, pp 3–25

    Google Scholar 

  3. Shall S (1984a) Inhibition of DNA repair by inhibitors of nuclear ADP-ribosyl transferase. Nucleic Acids Res Symp Ser 13:143–191

    CAS  Google Scholar 

  4. Shall S (1984b) ADP-ribose in DNA repair: A new component of DNA excision repair. Adv Radiat Biol 11:1–69

    CAS  Google Scholar 

  5. Whish WJD, Davies MI, Shall S (1975) Stimulation of poly(ADP-ribose) polymerase activity by the antitumour antibiotic, streptozotocin. Biochem Biophys Res Commun 65:722–730

    Article  PubMed  CAS  Google Scholar 

  6. Goodwin PM, Lewis PJ, Davies MI, Skidmore CJ, Shall S (1978) The effect of gamma-radiation and neocarzinostatin on NAD and ATP levels in mouse leukaemia cells. Biochem Biophys Acta 543:576–582

    Article  PubMed  CAS  Google Scholar 

  7. Skidmore CJ, Davies MI, Goodwin PM, Halldorsson H, Lewis PJ, Shall S, Zia’ee A-A (1979) The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by γ-radiation and N-methyl-N-nitrosourea. Eur J Biochem 101:135–142

    Article  PubMed  CAS  Google Scholar 

  8. Durkacz BW, Omidiji O, Gray DA, Shall S (1980) (ADP-ribose)n participates in DNA excision repair. Nature (London) 283:593–596

    Article  CAS  Google Scholar 

  9. Gray DA, Durkacz BW, Shall S (1981) Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitrosourea. FEBS Lett 131:173–177

    Article  PubMed  CAS  Google Scholar 

  10. Durkacz BW, Irwin J, Shall S (1981a) The effect of inhibition of (ADP-ribose)n biosynthesis on DNA repair assayed by the nucleoid technique. Eur J Biochem 121:65–69

    Article  PubMed  CAS  Google Scholar 

  11. Durkacz BW, Irwin J, Shall S (1981b) Inhibition of (ADP-ribose)n biosynthesis retards DNA repair but does not inhibit DNA repair synthesis. Biochem Biophys Res Commun 101:1433–1441

    Article  PubMed  CAS  Google Scholar 

  12. Creissen D, Shall S (1982) Regultion of DNA ligase activity by poly(ADP-ribose). Nature (London) 296:271–272

    Article  CAS  Google Scholar 

  13. Murray B, Irwin J, Creissen D, Tavassoli M, Durkacz BW, Shall S (to be published) Isolation and characterisation of cell variants altered in DNA ligase activity

    Google Scholar 

  14. Nduka N, Skodmore CJ, Shall S (1980) The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of γ-radiation by inhibitors of poly(ADP-ribose) polymerase. Eur J Biochem 105:515–530

    Article  Google Scholar 

  15. Farzaneh F, Shall S, Zalin R (1980) DNA strand breaks and poly(ADP-ribose) polymerase activity during chick muscle differentiation. In: Smulson M, Sugimura T (eds) Novel ADP-ribosylation of regulatory enzymes and proteins. Elsevier/North Holland, Amsterdam New York, pp 217–225

    Google Scholar 

  16. Farzaneh F, Zalin R, Brill D, Shall S (1982) DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation. Nature (London) 300:362–366

    Article  CAS  Google Scholar 

  17. Farzaneh F, Zalin R, Shall S (1964) Single-strand DNA breaks are formed during muscle cell differentiation. Exp Biol Med 9:260–268

    Google Scholar 

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© 1985 Springer-Verlag Berlin Heidelberg

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Shall, S. (1985). ADP-Ribosylation as a Cellular Control Mechanism. In: Althaus, F.R., Hilz, H., Shall, S. (eds) ADP-Ribosylation of Proteins. Proceedings in Life Sciences. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70589-2_2

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  • DOI: https://doi.org/10.1007/978-3-642-70589-2_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70591-5

  • Online ISBN: 978-3-642-70589-2

  • eBook Packages: Springer Book Archive

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