ADP-Ribosylation as a Cellular Control Mechanism

  • Sydney Shall
Part of the Proceedings in Life Sciences book series (LIFE SCIENCES)

Abstract

It is now about 21 years since the discovery of poly(ADP-ribose). This coming of age is reflected also in the interest and importance of ADP-ribosylation reactions in cell and molecular biology.

Keywords

Sedimentation Acetylcholine Creatine Thymidine Plasmodium 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Shall S. Durkacz BW, Gray DA, Irwin J, Lewis PJ, Perera M, Tavassoli M (1982) (ADP-ribose)n participates in DNA excision repair. In: Harris CC, Cerutti PA (eds) Mechanisms of chemical carcinogenesis. Liss, New York, pp 389–407Google Scholar
  2. 2.
    Shall S (1983) ADP-ribosylation, DNA repair, cell differentiation and cancer. In: Miwa M, Hayaishi O, Shall S, Smulson M, Sugimura T (eds) ADP-ribosylation, DNA repair and cancer. Jpn Sci Soc Press, Tokyo, pp 3–25Google Scholar
  3. 3.
    Shall S (1984a) Inhibition of DNA repair by inhibitors of nuclear ADP-ribosyl transferase. Nucleic Acids Res Symp Ser 13:143–191Google Scholar
  4. 4.
    Shall S (1984b) ADP-ribose in DNA repair: A new component of DNA excision repair. Adv Radiat Biol 11:1–69Google Scholar
  5. 5.
    Whish WJD, Davies MI, Shall S (1975) Stimulation of poly(ADP-ribose) polymerase activity by the antitumour antibiotic, streptozotocin. Biochem Biophys Res Commun 65:722–730PubMedCrossRefGoogle Scholar
  6. 6.
    Goodwin PM, Lewis PJ, Davies MI, Skidmore CJ, Shall S (1978) The effect of gamma-radiation and neocarzinostatin on NAD and ATP levels in mouse leukaemia cells. Biochem Biophys Acta 543:576–582PubMedCrossRefGoogle Scholar
  7. 7.
    Skidmore CJ, Davies MI, Goodwin PM, Halldorsson H, Lewis PJ, Shall S, Zia’ee A-A (1979) The involvement of poly(ADP-ribose) polymerase in the degradation of NAD caused by γ-radiation and N-methyl-N-nitrosourea. Eur J Biochem 101:135–142PubMedCrossRefGoogle Scholar
  8. 8.
    Durkacz BW, Omidiji O, Gray DA, Shall S (1980) (ADP-ribose)n participates in DNA excision repair. Nature (London) 283:593–596CrossRefGoogle Scholar
  9. 9.
    Gray DA, Durkacz BW, Shall S (1981) Inhibitors of nuclear ADP-ribosyl transferase retard DNA repair after N-methyl-N-nitrosourea. FEBS Lett 131:173–177PubMedCrossRefGoogle Scholar
  10. 10.
    Durkacz BW, Irwin J, Shall S (1981a) The effect of inhibition of (ADP-ribose)n biosynthesis on DNA repair assayed by the nucleoid technique. Eur J Biochem 121:65–69PubMedCrossRefGoogle Scholar
  11. 11.
    Durkacz BW, Irwin J, Shall S (1981b) Inhibition of (ADP-ribose)n biosynthesis retards DNA repair but does not inhibit DNA repair synthesis. Biochem Biophys Res Commun 101:1433–1441PubMedCrossRefGoogle Scholar
  12. 12.
    Creissen D, Shall S (1982) Regultion of DNA ligase activity by poly(ADP-ribose). Nature (London) 296:271–272CrossRefGoogle Scholar
  13. 13.
    Murray B, Irwin J, Creissen D, Tavassoli M, Durkacz BW, Shall S (to be published) Isolation and characterisation of cell variants altered in DNA ligase activityGoogle Scholar
  14. 14.
    Nduka N, Skodmore CJ, Shall S (1980) The enhancement of cytotoxicity of N-methyl-N-nitrosourea and of γ-radiation by inhibitors of poly(ADP-ribose) polymerase. Eur J Biochem 105:515–530CrossRefGoogle Scholar
  15. 15.
    Farzaneh F, Shall S, Zalin R (1980) DNA strand breaks and poly(ADP-ribose) polymerase activity during chick muscle differentiation. In: Smulson M, Sugimura T (eds) Novel ADP-ribosylation of regulatory enzymes and proteins. Elsevier/North Holland, Amsterdam New York, pp 217–225Google Scholar
  16. 16.
    Farzaneh F, Zalin R, Brill D, Shall S (1982) DNA strand breaks and ADP-ribosyl transferase activation during cell differentiation. Nature (London) 300:362–366CrossRefGoogle Scholar
  17. 17.
    Farzaneh F, Zalin R, Shall S (1964) Single-strand DNA breaks are formed during muscle cell differentiation. Exp Biol Med 9:260–268Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • Sydney Shall
    • 1
  1. 1.Cell and Molecular Biology Laboratory, Biology BuildingUniversity of SussexBrightonGreat Britain

Personalised recommendations