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Infarktgrößenbestimmung mittels Kontrastecho und Analyse der regionalen Wandbewegung

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Fortschritte der Echokardiographie
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Zusammenfassung

Die Injektion von Wasserstoffperoxyd (H2O2) in die Aortenwurzel bewirkt beim Hund eine echokardiographisch (2D-Echokardiographie) sichtbare Kontrastierung des Myokards und eine Kontrastaussparung bei Perfusionsunterbrechung.

Zur Infarktgrößenbeurteilung mittels 2D-Echokardiographie wurden bei 9 Hunden vor der Okklusion einer Kranzarterie und 6 h danach ca. 2,5 ml 0,3% iges H2O2 aortal injiziert, die Kontrastaussparung (KA) planimetriert und die regionale Kontraktion (RK) in der kurzen Ventrikelachse nach einem aus 48 Radianten bestehenden Modell quantifiziert. Die Ergebnisse wurden dem mittels Triphenyltetrazoliumchlorid identifizierten Infarktareal (TTC) gegenübergestellt.

Zwischen histochemisch bestimmter Infarktgröße und Kontrastaussparung bestand eine enge Korrelation von r = 0,98.

Mittels Analyse der regionalen Wandbewegung wurde bei ebenfalls guter Korrelation (r = 0,88) das Ausmaß des Infarkts um etwa 10% überschätzt.

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© 1985 Springer-Verlag Berlin Heidelberg

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Störger, H., Reifart, N., Khuri, S., Kaltenbach, M. (1985). Infarktgrößenbestimmung mittels Kontrastecho und Analyse der regionalen Wandbewegung. In: Erbel, R., Meyer, J., Brennecke, R. (eds) Fortschritte der Echokardiographie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70564-9_15

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  • DOI: https://doi.org/10.1007/978-3-642-70564-9_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70565-6

  • Online ISBN: 978-3-642-70564-9

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