In Vivo Performance of an Intravascular pH Monitoring Catheter
Continuous monitoring of blood pH has a great potential for application in various clinical disciplines. Intravascular pH monitoring can be important in both diagnostic and therapeutic medicine. Cobbe and Poole-Wilson  have demonstrated that the pH of the coronary sinus effluent is a diagnostic tool in the process of determining obstructions in coronary arteries. They also state that monitoring of intra-arterial blood pH can be used as an early warning system for critically ill patients such as those with severe hemorrhagic shock, in whom abrupt changes in pH may occur. Blood with a low pH may facilitate the occurrence of certain cardiac arrhythmias. Thus, maintaining a normal arterial pH is of value in the prevention and treatment of rhythm disturbances . Especially when cardiopulmonary bypass is employed, continuous pH monitoring has been considered a real asset because the biochemical changes in these patients are rapid and progressive . Camilli  has tried to use implantable pH electrodes as sensors for the control of the stimulation rate of an artificial cardiac pacemaker. Also, for physiological research, continuous intraarterial pH measurements have been proved to be meaningful .
KeywordsCatheter Epoxy Heparin Bicarbonate Fentanyl
Unable to display preview. Download preview PDF.
- 3.Bousse LJ (1982) The chemical sensitivity of electrolyte/insulator/silicon structure. Ph D thesis, Twente University of Technology, The NetherlandsGoogle Scholar
- 4.Camilli L, Alcidi L, Papeschi G (1976) A new pacemaker autoregulating the rate of pacing in relation to metabolic needs. Proc 5th Int Symp Card Pacing Tokyo: 414–418Google Scholar
- 5.Cobbe SM, Poole-Wilson PA (1979) Continuous measurement of pH in central arteries and veins. Lancet I: 444–445Google Scholar
- 7.De Rooij NF, Bergveld P (1980) Iridium/anodic iridium oxide film electrode as a pH sensor. Monitoring of Vital Parameters during Extracorporeal Circulation Proc Int Conf, Nijmegen pp 156–165Google Scholar
- 9.Le Blanc OH, Brown JF, Klebe JF, Niedrach LW, Slusarczuk GMJ, Stoddard WH (1976) Polymer membrane sensors for continuous intravascular monitoring of blood pH. J Appl Physiol 40: 644–647Google Scholar
- 11.O’Brien EN (1967) Blood gas and acid base changes in cardiac surgery. Bio-Medical Engineering 2: 407–409Google Scholar
- 13.Oeseburg B, Kwant G, Rispens P, Schut JK (1982) Continuous intra-aortic pH measurement in dogs. In: Oeseburg B, Zijlstra WG (eds) Methodology and physiology of blood gases and pH. Private Press, GroningenGoogle Scholar