A New Potential Electrode for Glucose Measurements

Kessler, M.; Höper, J.

doi:10.1007/978-3-642-70518-2_12

M. Kessler &
J. Höper

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Abstract

The function of the first electrochemical glucose sensor, described in 1962 by Clark and Lyons [1], is based on the principle of oxidation of glucose in the presence of dissolved oxygen by glucose oxidase (GOD) to form gluconic acid and hydrogen peroxide. In such a Clark-type electrode system, called an enzyme electrode by Updike and Hicks [3], either the decrease in dissolved oxygen consumed by the enzyme reaction or the formation of hydrogen peroxide generated as a product of the degradation of glucose is measured by amperometric polarography.

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References

Clark LC Jr, Lyons C (1962) Electrode systems for continuous monitoring in cardiovascular surgery, Ann NY Acad Sci 102: 29–45
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Kessler M, Hoper J (1978) Oxygen electrodes — a brief review, In: Dutton PL, Leigh JS, Scarpa A (eds) Frontiers of biological energetics, vol 2. Academic, New York
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Updike SJ, Hicks GP (1967) The enzyme electrode, a miniature chemical transducer using immobilized enzyme activity. Nature 214: 986–988
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Authors

M. Kessler
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J. Höper
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Editors and Affiliations

Institut för Physiologie und Kardiologie, Waldstr. 6, D-8520, Erlangen, Germany
Manfred Kessler , David Keith Harrison & Jens Höper , &
Dept. of Chemistry, University of North Carolina, Chapel Hill, NC, 27514, USA
R. P. Buck
Dept. of Physiology, School of Medicine, The Center for Health Science, University of California, Los Angeles, California, 90024, USA
G. Eisenman
Biosensors Inc., PO Box 640, Chester, New Jersey, 07930, USA
J. Hill
Faculty of Medicine, American Univ. of Beirut, Beirut, Lebanon
R. N. Khuri
Direktor des Max-Planck-Instituts für Systemphysiologie, Rheinlanddamm 201, 4600, Dortmund 1, Germany
D. W. Lübbers
Medical Center, Dept. of Physiology and Biophysics, New York University, 550 First Avenue, New York, NY, 10016, USA
C. Nicholson
Laboratorium für Organische Chemie, Universitätsstr. 16, 6000, Frankfurt M. 70, Germany
W. Simon
The Middlesex Hospital, Mortimer St., London W N, 8AA, England
T. Treasure
Institute of Medical Physiology, Dept. A, University of Copenhagen, DK-2200, Copenhagen N, Denmark
T. Zeuthen

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Kessler, M., Höper, J. (1985). A New Potential Electrode for Glucose Measurements. In: Kessler, M., et al. Ion Measurements in Physiology and Medicine. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70518-2_12

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DOI: https://doi.org/10.1007/978-3-642-70518-2_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-15468-6
Online ISBN: 978-3-642-70518-2
eBook Packages: Springer Book Archive

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