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A Neurologist’s View of Nausea and Vomiting

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Book cover Nausea and Vomiting: Mechanisms and Treatment

Part of the book series: Advances in Applied Neurological Sciences ((NEUROLOGICAL,volume 3))

Abstract

The mechanisms (and treatment) of sickness depend on the cause. Some of the neurological causes of vomiting are the following (see also Table 1):

  1. 1.

    Migraine. Classic migraine attacks are characterised by nausea, and also by gastric stasis. Intense pain may contribute to gastric stasis, which may be the cause of the sensation of nausea, and may or may not lead to vomiting. Moreover, it is possible that the effect of analgesics is increased by administration of an anti-emetic.

  2. 2.

    Raised intracranial pressure. Vomiting may be sudden and forceful, but more often is preceded by severe nausea. Relief of raised pressure (e.g. surgery, dexamethasone) relieves sickness within a few days.

  3. 3.

    Low brain-stem focal gliomas. These may cause severe and persistent vomiting, with or without nausea, in the early stages, and without raised intracranial pressure, pointing to a vomiting centre in man localized in the low medulla.

  4. 4.

    Vestibular disorders. Vomiting is a common feature in ear disease, Meniere’s disease, vestibular neuronitis. Anticholinergic and antihistaminic, but not antidopaminergic, drugs give relief.

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Authors and Affiliations

  1. Department of Neurology, King’s College Hospital and Institute of Psychiatry, University of London, Denmark Hill, London, SE5, UK

    J. D. Parkes

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  1. J. D. Parkes
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Editor information

Editors and Affiliations

  1. Royal Navy, Corpus Christi College, Oxford, UK

    Christopher J. Davis BSc (Hons), MB, BS, AKC (Surgeon Lieutenant Commander, Senior Specialist in Applied Physiology (Royal Navy) and Research Training Fellow) (Surgeon Lieutenant Commander, Senior Specialist in Applied Physiology (Royal Navy) and Research Training Fellow)

  2. University Department of Clinical Pharmacology, Radcliffe Infirmary, OX2 6HE, Oxford, UK

    Christopher J. Davis BSc (Hons), MB, BS, AKC (Surgeon Lieutenant Commander, Senior Specialist in Applied Physiology (Royal Navy) and Research Training Fellow) (Surgeon Lieutenant Commander, Senior Specialist in Applied Physiology (Royal Navy) and Research Training Fellow)

  3. Medical Department, Janssen Pharmaceutical Ltd (UK), OX12 ODQ, Wantage Oxfordshire, UK

    Gerry V. Lake-Bakaar BSc (Hons), MD, MRCP (Research Gastroenterology Physician and Director of Medical Affairs) (Research Gastroenterology Physician and Director of Medical Affairs)

  4. University of Oxford, Oxford, UK

    David G. Grahame-Smith MA, MB, BSc, PhD, FRCP (Rhodes Professor of Clinical Pharmacology, Fellow of Corpus Christi College, Honorary Director of the MRC Clinical Pharmacology Unit, Radcliffe Infirmary, Oxford and Honorary Consultant, Physician) (Rhodes Professor of Clinical Pharmacology, Fellow of Corpus Christi College, Honorary Director of the MRC Clinical Pharmacology Unit, Radcliffe Infirmary, Oxford and Honorary Consultant, Physician)

  5. General Internal Medicine and Clinical Pharmacology, Oxford Health Authority, OX2 6HE, Oxford, UK

    David G. Grahame-Smith MA, MB, BSc, PhD, FRCP (Rhodes Professor of Clinical Pharmacology, Fellow of Corpus Christi College, Honorary Director of the MRC Clinical Pharmacology Unit, Radcliffe Infirmary, Oxford and Honorary Consultant, Physician) (Rhodes Professor of Clinical Pharmacology, Fellow of Corpus Christi College, Honorary Director of the MRC Clinical Pharmacology Unit, Radcliffe Infirmary, Oxford and Honorary Consultant, Physician)

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© 1986 Springer-Verlag Berlin Heidelberg

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Parkes, J.D. (1986). A Neurologist’s View of Nausea and Vomiting. In: Davis, C.J., Lake-Bakaar, G.V., Grahame-Smith, D.G. (eds) Nausea and Vomiting: Mechanisms and Treatment. Advances in Applied Neurological Sciences, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70479-6_12

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  • DOI: https://doi.org/10.1007/978-3-642-70479-6_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70481-9

  • Online ISBN: 978-3-642-70479-6

  • eBook Packages: Springer Book Archive

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