Adaptation is the modulation of the visual transduction process by prior illumination. Accordingly, its understanding depends on and contributes to understanding of the visual transduction process itself. Unfortunately, this mutual influence has not yet been very fruitful, perhaps because it calls for at least the beginnings of a complete model of the transduction process. Most of the work on adaptation, some highlights of which are reported here, have therefore been studies of the phenomenology of adaptation and of the chemicals which directly intermediate it. These studies are still largely groping in the dark, especially in vertebrates, and are therefore necessarily more tentative and less focussed than those of the transduction process itself, about which more is known. The formulation of open questions with which this report ends suggests, however, that the time has come when the state of our biochemical understanding of the transduction process (Chabre and Applebury and Applebury et al., both this volume) will make possible direct exploitation of the constraints imposed by adaptational data.
KeywordsVisual Pigment Light Adaptation Group Report Adaptational Transmitter Turtle Retina
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- (6).Borsellino, A.; Fuortes, M.G.F.; and Smith, T.G. 1965. Visual responses in Limulus. Cold S.H. Symp. Quant. Biol. 30: 429–443.Google Scholar
- (32).Stieve, H.; Pflaum, M.; Klomfaß, J.; and Gaube, H. 1985. Calcium/ sodium binding competition in the gating of light-activated membrane conductance studied by voltage clamp technique in Limulus ventral nerve photoreceptor. Z. Naturforsch. 40c: 278–291.Google Scholar
- (11).Claßen-Linke, I., and Stieve, H., 1981. Time course of dark adaptation in the Limuls ventral nerve photoreceptor — measured as constant response amplitude curve — and its dependence upon extracellular calcium. Biophys. Struct. Mech. 7: 336–337.Google Scholar
- (8).Brown, J.E., and Rubin, L.J. 1985. Inositol trisphosphate induces an increase in intracellular ionized calcium in intact and functioning Limulus photoreceptors. Biophys. J. 47: 38 (Abstract).Google Scholar
- (15).Fuortes, M.G.F., and Hodgkin, A.L. 1964. Changes in time scale and sensitivity in the ommatidia of Limulus. J. Phyisol. 172: 239–263.Google Scholar
- (12).Corson, D.W.; Fein, A.; and Payne, R. 1984. Detection of an inositol 1, 4, 5 trischosphate-induced rise in intracellular free calcium with aequorin m Limulus ventral photoreceptors. Biol. Bull. 167: 524 (Abstract).Google Scholar
- (19).Hamdorf, K. 1979. The physiology of invertebrate visual pigments. In Handbook of Sensory Physiology. Comparative Physiology and Evolution of Vision in Invertebrates. A. Invertebrate Photoreceptors, ed. H. Autrum, vol. 7, pt. 6A, pp. 145–224. Berlin: Springer-Verlag.Google Scholar
- (17).Grzywacz, N.M. 1985. On individual and interactive properties of the single photon responses in invertebrate photoreceptors. Ph.D. Thesis, Hebrew University, Jerusalem.Google Scholar
- (23).Ivens, I., and Stieve, H. 1984. Influence of the membrane potential on the intracellular light induced Ca2+ concentration change of the Limulus ventral photoreceptor monitored by Arsenazo III under voltage clamp conditions. Z. Naturforsch. 39c: 985–992.Google Scholar
- (28).Lisman, J.E. 1984. Properties of visual pigment off-switch. Inv. Ophthalmol. Vis. Sci. 25: 157.Google Scholar
- (24).Keiper, W.J.M.; Schnakenberg, J.; and Stieve, H. 1984. Statistical analysis of quantum bump parameters in Limulus ventral photoreceptors. Z. Naturforsch. 39c: 781–790.Google Scholar
- (39).Stieve, H.; Bruns, M.; and Gaube, H. 1984. The sensitivity shift due to light adaptation depending on the extracellular calcium ion concentration in Limulus ventral nerve photoreceptor. Z. Naturforsch. 39c: 662–679.Google Scholar