Blood Groups

  • Otto G. Bier


The blood has always been regarded by man as an object of mystery and fascination — a vitalizing and rejuvenating element. Even ancient authors reported transferring the blood of animals, usually of sheep and dogs, to man. They noted that such transfusions invariably resulted in fever and hemoglobinuria, and terminated not infrequently in the death of the patient. Blundell (1818), who can be considered the father of the modern blood transfusion, recognized that when the recipient and the donor were of the same species, e.g., dog-to-dog or human-to-human transfusions, the tolerance was greater, although even then there were numerous accidents. The problem was not resolved until 1900, when Landsteiner, having discovered the blood groups of the ABO system, interpreted the post-transfusion reactions in terms of an interaction between the red cells of the donor and isoantibodies (or more properly, alloantibodies) existing in the serum of the recipient.


Blood Group Autoimmune Hemolytic Anemia Group Substance Blood Group Substance Erythrocytic Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Amos DB, Ward FE (1975) Immunogenetics of the HL-A system. Physiol Rev 5: 271Google Scholar
  2. Boyd WC (1963) The lectins: Their present status. Vox Sang (Basel) 8: 1CrossRefGoogle Scholar
  3. Fisher RA (1947) The rhesus factor. Am Sci 35:95Google Scholar
  4. Goudemand M, Delmas-Marsalet Y ( 1967 ) Eléments de Immunohématologie. Flammarion, ParisGoogle Scholar
  5. Kabat EA (1956) Blood group substances, their chemistry and immunochemistry. Academic, New YorkGoogle Scholar
  6. Kabat EA (1976) Structural concepts in immunology and immunochemistry. Holt, Rinehart & Winston, New YorkGoogle Scholar
  7. Levine P (1951) A brief review of the newer blood factors. Trans NY Acad Sci Sect II 13: 205Google Scholar
  8. Marcus DM (1969) The ABO and Lewis blood group system. Immunochemistry, genetics, and relation to disease. N Engl J Med 280: 994PubMedCrossRefGoogle Scholar
  9. Mollison PL (1967) Blood transfusion in clinical medicine. Blackwell, OxfordGoogle Scholar
  10. Morgan WTJ (1960) Croonian lecture: A contribution to human biochemical genetics. Proc Roy Soc B 151: 308CrossRefGoogle Scholar
  11. Post RH, et al. (1968) Tabulations of phenotype and gene frequencies for 11 different genetic systems studied in the American Indian. In: Biomedical challenges presented by the Indian. PAHO/WHO, WashingtonGoogle Scholar
  12. Prokop O, Uhlenbruck G (1969) Human blood and serum groups. McLauren, LondonGoogle Scholar
  13. Race R R, Sanger R (1968) Blood groups in man, 5th edn. Blackwell, OxfordGoogle Scholar
  14. Schiff F, Boyd WC (1942) Blood grouping technic. Interscience, New YorkGoogle Scholar
  15. Schwartz LM, Miles W (1972) Blood Bank Technology, 2nd Ed. Williams & Wilkins, BaltimoreGoogle Scholar
  16. Springer GF (1971) Blood-group and Forrsman-anti- genic-determinants shared between microbes and mammalian cells. Prog Allergy 15: 19Google Scholar
  17. Watkins W (1966) Blood group substances. Science 152: 172PubMedCrossRefGoogle Scholar
  18. Wiener AS (1946) Blood groups and blood transfusion.C C Thomas, Springfield, 111.Google Scholar
  19. Wiener AS, Wexler IB (1958) Heredity of the blood groups. Grune & Strattan, New YorkGoogle Scholar
  20. Zmijewski CM (1968) Immunohematology. Appleton- Century-Crofts, New YorkGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1986

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  • Otto G. Bier

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