Control of infectious diseases by immuno-therapy and chemotherapy has made possible the survival of individuals genetically predisposed to a series of diseases including immunodeficiencies that formerly resulted in death before the individual reached reproductive age. As a result, today, rare genes are expressed, which formerly were the exception. Thus, immunodeficiencies may cease to be rare diseases in the not too distant future.
KeywordsChronic Granulomatous Disease Purine Nucleoside Phosphorylase Complement Deficiency Chronic Lymphatic Leukemia Heavy Chain Disease
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