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The Rhino Mouse: Retinoid Effects on a Model of Keratin Accumulation

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Book cover Skin Models

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Abstract

The skin of the rhino mouse is characterized by numerous large cysts of two types: superficial cysts termed utricles, and deeper cysts. The utricles are derived from the hair canals and open to the surface. The squamous epithelium of these is continuous with the surface epidermis, and produces keratin which is found in the cyst cavity. A sebaceous gland lies at their base. The underlying cysts situated in the subcutaneous fat are derived from the hair root sheath epithelium and are lined with keratinizing epithelium [5].

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References

  1. Ashton RE, Connor MJ, Lowe NJ (1984) Histologic changes in the skin of the rhino mouse (hrrh hrrh) induced by retinoids. J Invest Dermatol 82: 632–635

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  5. Howard A (1940) “Rhino”, an allele of hairless in the house mouse. J Hered 31:467–470

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Authors
  1. R. E. Ashton
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  2. N. J. Lowe
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Editor information

Editors and Affiliations

  1. Department of Medicine, University of Wales College of Medicine, Health Park, CF4 4XN, Cardiff, UK

    Ronald Marks

  2. Universitäts-Hautklinik Düsseldorf, Moorenstr. 5, D-4000, Düsseldorf 1, Germany

    Gerd Plewig

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© 1986 Springer-Verlag Berlin Heidelberg

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Ashton, R.E., Lowe, N.J. (1986). The Rhino Mouse: Retinoid Effects on a Model of Keratin Accumulation. In: Marks, R., Plewig, G. (eds) Skin Models. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-70387-4_5

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  • DOI: https://doi.org/10.1007/978-3-642-70387-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-70389-8

  • Online ISBN: 978-3-642-70387-4

  • eBook Packages: Springer Book Archive

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