Skin Models pp 412-419 | Cite as

In Vitro Test Systems for Evaluation of the Physical Properties of the Skin

  • H. G. Vogel


Despite several attempts [1–12, 15] to describe the mechanical behaviour of skin by a mathematical model none of them has been proven to be sufficient for evaluation of all properties including the history before measurement and the time-dependence during measurement. Therefore several methods have to be applied to investigate different aspects of biorheology.


Body Axis Cyclic Strain Mechanical Recovery Initial Tension Creep Experiment 
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  1. 1.
    Anna O, Arnold G, Hartung C, Zech M (1974) Biomechanik and Simulation des Zugverhaltens der Chordae tendinae des menschlichen Herzens. J Mat Technol 5: 209–217Google Scholar
  2. 2.
    Danielson DA (1973) Human skin as an elastic membrane. J Biomechanics 6: 539–546CrossRefGoogle Scholar
  3. 3.
    Frisen M, Magi M, Sonnerup L, Viidik A (1969) Rheological analysis of soft collagenous tissue, Part I: Theoretical considerations. J Biomechanics 2: 13–20CrossRefGoogle Scholar
  4. 4.
    Frisen M, Magi M, Sonnerup L, Viidik A (1969) Theological analysis of soft collagenous tissues, Part II: Experimental evaluations and verifications. J Biomechanics 2: 21–28CrossRefGoogle Scholar
  5. 5.
    Fung YC (1981) Biomechanics. Mechanical properties of living tissue. Springer, New YorkGoogle Scholar
  6. 6.
    Hirsch C, Sonnerup L (1968) Macroscopic rheology in collagen material. J Biomechanics 1: 13–18CrossRefGoogle Scholar
  7. 7.
    Jamison CE, Marangoni RC, Glaser AA (1968) Viscoelastic properties of soft tissue by discrete model characterization. J Biomechanics 1: 33–46CrossRefGoogle Scholar
  8. 8.
    Jenkins RB, Little RW (1974) A constitutive equation for parallel-fibered elastic tissue. J Biomechanics 7: 397–402CrossRefGoogle Scholar
  9. 9.
    Lanir Y, Fung YC (1974) Two-dimensional mechanical properties of rabbit skin. II. Experimental results. J Biomechanics 7: 171–182CrossRefGoogle Scholar
  10. 10.
    Sanjeevi R (1982) A viscoelastic model for the mechanical properties of bilogical materials. J Biomechanics 2: 107–118CrossRefGoogle Scholar
  11. 11.
    Soong TT, Huang WN (1973) A stochastic model for biological tissue elasticity in simple elongation. J Biomechanics 6: 451–485CrossRefGoogle Scholar
  12. 12.
    Veronda DR, Westmann RA (1970) Mechanical characterization of skin-finite deformations. J Biomechanics 3: 111–124CrossRefGoogle Scholar
  13. 13.
    Vogel HG (1972) Influence of age, treatment with corticosteroids and strain rate on mechanical properties of rat skin. Biochim Biophys Acta 286: 79–83PubMedCrossRefGoogle Scholar
  14. 14.
    Vogel HG (1973) Stress relacation in rat skin after treatment with hormones. J Med 4: 19–27PubMedCrossRefGoogle Scholar
  15. 15.
    Vogel HG (1976) Measurement of some viscoelastic properties of rat skin following repeated load. Conn Tiss Res 4: 163–168CrossRefGoogle Scholar
  16. 16.
    Vogel HG (1976) Altersabhängige Veränderungen der mechanischen and biochemischen Eigenschafte der Cutis bei Ratten. Akt Gerontol 6: 477–487Google Scholar
  17. 17.
    Vogel HG (1976) Mechanical parameters in rat skin following repeated load. Influence of age and corticosteroid treatment. G-I-T 20: 113–121Google Scholar
  18. 18.
    Vogel HG (1976) Tensile strength, relaxation and mechanical recovery in rat skin as influenced by maturation and age. J Med 2: 177–188Google Scholar
  19. 19.
    Vogel HG (1977) Strain of rat skin at constant load (creep experiments). Influence of age and desmotropic agents. Gerontology 23: 77–86PubMedCrossRefGoogle Scholar
  20. 20.
    Vogel HG (1978) Influence of maturation and age on mechanical and biochemical parameters of connective tissue of various organs in the rat. Conn Tiss Res 6: 161–166CrossRefGoogle Scholar
  21. 21.
    Vogel HG (1978) Age dependence of mechanical parameters in rat skin following repeated strain. Akt gerontol 11: 601–618Google Scholar
  22. 22.
    Vogel HG (1981) Directional variations of mechanical parameters in rat skin depending on maturation and age. J Invest Dermatol 76: 493–497PubMedCrossRefGoogle Scholar
  23. 23.
    Vogel HG (1983) Age dependence of visoelastic properties in rat skin. Directional variations in stress-strain and hysteresis experiments. Bioeng Skin 2: 136–155Google Scholar
  24. 24.
    Vogel HG (1985) Repeated relaxation and determination of the isorheological point in skin strips of rats as being influenced by maturation and aging. Bioeng Skin 1: 321–335Google Scholar
  25. 25.
    Vogel HG, Hilgner W (1977) Analysis of the low part of stress-strain curves in rat skin. Influence of age and desmotropic drugs. Arch Dermatol Res 258: 141–150PubMedCrossRefGoogle Scholar
  26. 26.
    Vogel HG, Hilgner W (1978) Viscoelastic behaviour or rat skin after repeated and stepwise ncreased strain. Bioengineering and the skin 2: 22–23Google Scholar
  27. 27.
    Vogel HG, Hilgner W (1979) The “step phenomenon” as observed in animal skin. J Biomechanics 12: 75–81CrossRefGoogle Scholar
  28. 28.
    Vogel HG, Hilgner W (1979) Influence of age and of desmotropic drugs on the step phenomenon observed in rat skin. Arch Dermatol Res 264: 225–241PubMedCrossRefGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1986

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  • H. G. Vogel

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