Use of In Vivo and In Vitro Test Systems as Predictors of the Cutaneous Irritancy of Synthetic Detergents (Syndets)
There have been several attempts to develop laboratory or animal based test systems [6, 8, 12, 14] which might prove useful either in the prediction of irritancy of synthetic detergents (syndets) in humans or in discriminating between different syndets. The degrees of success of these methods have been variable and the search continues for more suitable techniques.
KeywordsStratum Corneum Rank Order Synthetic Detergent Human Fibroblast Culture Laboratory Base Method
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