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Skin Models pp 218-236 | Cite as

The Development of Epidermis In Vitro. Electronmicroscopic and Autoradiographic Studies in the Limb Bud Culture

  • U. Schultz-Ehrenburg
Conference paper

Abstract

A problem of epidermal culture systems is to obtain organotypical differentiation in vitro. For that purpose, the presence of dermal factors is of great importance. The epithelio-mesenchymal interaction is best presented in organ cultures of skin, but adult skin explants show short survival times and a progressive loss of maturation. The most successful culture condition is the embryonal organ culture because it is able not only to survive and to grow, but also to differentiate and to mature.

Keywords

Stratum Corneum Basal Cell Layer Stratum Granulosum Apical Ectodermal Ridge Glycoprotein Synthesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • U. Schultz-Ehrenburg

There are no affiliations available

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