Discrimination of Leukemias, Lymphomas, and Non-Neoplastic Controls by Retroviral Serum Markers
Diagnostic and prognostic markers are urgently needed for early diagnosis and therapy of malignant neoplasias. One Solution of this problem is the search for etiologic factors in the hope that they might indicate the presence or degree of progression of the disease. One possible factor are the retroviruses which are known to cause certain malignancies in several animal species . These malignancies include leukemias, lymphomas, and sarcomas. Footprints of retroviruses have also been repeatedly described in man, and retroviral isolates have been grown from human neoplastic and non-neoplastic cells. These viral isolates include not only the human T lymphotropic viruses (HTLV-I-III), but also viruses that are very similar to the primate retroviruses simian sarcoma virus (SiSV) and baboon endogenous virus (BaEV) [2, 3, 6].
KeywordsLymphoma Leukemia Sarcoma Nash Sera
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