Red Cell Transfusions for Polytransfused Patients

  • S. F. Goldmann
Conference paper
Part of the Haematology and Blood Transfusion / Hämatologie und Bluttransfusion book series (HAEMATOLOGY, volume 29)


Patients with chronic anemia tolerate much lower leveis of hemoglobin than those experiencing acute blood loss or acute hemolysis. The compensating mechanism is the increase of red cell 2,3-diphosphoglycerate (DPG), causing increased release of oxygen to the tissues. For this and further clinical and epidemiologic reasons, it is unnecessary to transfuse patients with chronic anemia unless symptoms of anoxia are expressed. This rarely odcurs at hemoglobin leveis higher than 8 g/dl. Many patients tolerate lower leveis of hemoglobin and, therefore, do not require RBC transfusions.


Severe Combine Immunodeficiency Blood Unit Severe Aplastic Anemia Transfusion Reaction Chronic Anemia 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1985

Authors and Affiliations

  • S. F. Goldmann
    • 1
    • 2
  1. 1.Abteilung TransplantationsimmunologieDRK-Blutspendezentrale UlmUlmGermany
  2. 2.Abteilung TransfusionsmedizinUniversität UlmUlmGermany

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